Available data Protein details
MAP3K1
94a1045d-6228-41f7-84a1-e22092a448bb
Targeting drugs
The protein is currently assigned to 2 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB11967 Details Details
DrugBank Drug Name Binimetinib Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Values
The protein is currently assigned to 13 values.
# Data Value Internal External
HGNC ID 6848 Details Details
HGNC Symbol MAP3K1 Details -
HGNC Name mitogen-activated protein kinase kinase kinase 1 Details -
HGNC Alias MAPKKK1 Details -
HGNC Alias MEKK Details -
HGNC Alias MEKK1 Details -
Ensembl ID ENSG00000095015 Details Details
UniProt ID Q13233 Details Details
UniProt Title M3K1_HUMAN Details -
NCBI ID 4214 Details Details
InnateDB ID 22000 Details Details
DrugBank Drug ID DB11967 Details Details
DrugBank Drug Name Binimetinib Details -
Interactions
The protein is currently assigned to 132 interactions.
# Interaction Type Links
DYRK1A - MAP3K1 Target Details
MAP3K1 - AXIN1 Source Details
RAF1 - MAP3K1 Target Details
FLNB - MAP3K1 Target Details
MAP3K1 - RPS13 Source Details
MAP3K1 - GRB2 Source Details
MAP3K1 - MAPK8 Source Details
CDK5 - MAP3K1 Target Details
MAP3K1 - FOXP3 Source Details
MAP4K3 - MAP3K1 Target Details
AXIN1 - MAP3K1 Target Details
MAP3K1 - MAP4K4 Source Details
MAP3K1 - UBE2D4 Source Details
GRB2 - MAP3K1 Target Details
MAP3K1 - MAP3K1 Source Details
MAP3K1 - MAP3K1 Target Details
MAP3K1 - MAP2K1 Source Details
MAP3K1 - RPL4 Source Details
MAP3K1 - UBE2I Source Details
HNRNPK - MAP3K1 Target Details
MAP3K1 - SRPK2 Source Details
MAP3K1 - TRAF2 Source Details
RIPK1 - MAP3K1 Target Details
PKD1 - MAP3K1 Target Details
CHUK - MAP3K1 Target Details
MAPK8IP3 - MAP3K1 Target Details
BRAF - MAP3K1 Target Details
MAP3K1 - STK38 Source Details
PAK1 - MAP3K1 Target Details
MAP3K1 - HSP90AB1 Source Details
MAP3K1 - IKBKB Source Details
CHRM5 - MAP3K1 Target Details
MAP3K1 - DCAF7 Source Details
MAP3K1 - NOTCH1 Source Details
MAP3K14 - MAP3K1 Target Details
HRAS - MAP3K1 Target Details
MAP3K1 - HIPK2 Source Details
MAP3K1 - UBE2D1 Source Details
MAP3K1 - ZFP36 Source Details
NR4A1 - MAP3K1 Target Details
ARHGAP4 - MAP3K1 Target Details
MAP3K1 - TRIM5 Source Details
MAPK1 - MAP3K1 Target Details
BRCA1 - MAP3K1 Target Details
PAK2 - MAP3K1 Target Details
CASP3 - MAP3K1 Target Details
MAP3K1 - RPL30 Source Details
MAP3K1 - EPHA4 Source Details
MAP3K1 - NFKBIA Source Details
MAP3K1 - RAF1 Source Details
PPP2CA - MAP3K1 Target Details
TNIK - MAP3K1 Target Details
MAP3K1 - SMAD3 Source Details
RAC1 - MAP3K1 Target Details
MAP3K1 - MAP2K6 Source Details
JUN - MAP3K1 Target Details
MAP3K1 - ETS2 Source Details
MAP3K1 - MAPK14 Source Details
MAP3K1 - UBC Source Details
MAP3K1 - BAALC Source Details
MAP3K1 - FKBP5 Source Details
MAP3K1 - MAPK9 Source Details
LLGL2 - MAP3K1 Target Details
ETS1 - MAP3K1 Target Details
MAP2K1 - MAP3K1 Target Details
STK38 - MAP3K1 Target Details
HSP90AB1 - MAP3K1 Target Details
MAP3K1 - MAPK3 Source Details
MAP3K1 - MAFA Source Details
MAP3K1 - GRIPAP1 Source Details
MAP3K1 - UBE2D3 Source Details
MAP4K4 - MAP3K1 Target Details
MAP3K1 - MIS12 Source Details
MAP3K1 - FADD Source Details
MAP3K1 - UBE2L6 Source Details
HSPA1L - MAP3K1 Target Details
MAP3K1 - MAP2K7 Source Details
MAP3K1 - YWHAE Source Details
MAP3K1 - MAP4K1 Source Details
MAP3K1 - NOP56 Source Details
MAP3K1 - FRAT1 Source Details
MAP3K1 - MAP2K2 Source Details
MAP3K1 - PAK1 Source Details
MAP3K1 - MAP2K3 Source Details
MAP3K1 - HSP90AA1 Source Details
ACTN1 - MAP3K1 Target Details
IKBKB - MAP3K1 Target Details
MAP3K1 - IRS4 Source Details
TRAF2 - MAP3K1 Target Details
MAP3K1 - UBE2E1 Source Details
GSK3B - MAP3K1 Target Details
RHOA - MAP3K1 Target Details
MAP3K1 - YWHAQ Source Details
MAP3K1 - UBE2W Source Details
MAP4K1 - MAP3K1 Target Details
MAP3K1 - MAPK8IP3 Source Details
TNFRSF1A - MAP3K1 Target Details
HSP90AA1 - MAP3K1 Target Details
MAP3K1 - CEP85 Source Details
MAP3K1 - MAP4K2 Source Details
MAP3K1 - DYRK1B Source Details
FKBP5 - MAP3K1 Target Details
MAP3K1 - CRTC1 Source Details
MAP4K2 - MAP3K1 Target Details
MAP3K1 - MAPK1 Source Details
NRK - MAP3K1 Target Details
MAP4K5 - MAP3K1 Target Details
GSTP1 - MAP3K1 Target Details
GRIPAP1 - MAP3K1 Target Details
MAP3K1 - MAP2K4 Source Details
ARRB2 - MAP3K1 Target Details
MAP3K11 - MAP3K1 Target Details
MAP3K1 - PKD1 Source Details
ABL1 - MAP3K1 Target Details
MAP3K1 - MAP3K11 Source Details
MAP3K1 - STAT3 Source Details
ECSIT - MAP3K1 Target Details
MAP3K1 - CDC37 Source Details
DVL2 - MAP3K1 Target Details
MAP3K1 - NFATC3 Source Details
CDC42 - MAP3K1 Target Details
MAP3K1 - UBE2D2 Source Details
GATA2 - MAP3K1 Target Details
MAP3K1 - CHUK Source Details
ESR1 - MAP3K1 Target Details
MAP3K1 - SMAD2 Source Details
MAP3K1 - UBB Source Details
DTX1 - MAP3K1 Target Details
MAP3K1 - YWHAG Source Details
TRAF6 - MAP3K1 Target Details
MAP3K1 - TP53 Source Details
KRAS - MAP3K1 Target Details
Collections
The protein is currently assigned to 62 collections.
# Collection Links
Mutated genes for cell-line KMS20 Details
Mutated genes for cell-line BB49HNC Details
Mutated genes for cell-line MONOMAC1 Details
Mutated genes for cell-line KPNYS Details
Mutated genes for cell-line NCIH748 Details
Mutated genes for cell-line MCC142 Details
Mutated genes for cell-line HT3 Details
Mutated genes for cell-line CORL51 Details
Mutated genes for cell-line SW872 Details
Mutated genes for cell-line NY Details
Mutated genes for cell-line BE2M17 Details
Mutated genes for cell-line ICC15 Details
Mutated genes for cell-line RCK8 Details
Mutated genes for cell-line HCS2 Details
Mutated genes for cell-line P31FUJ Details
Mutated genes for cell-line SW579 Details
Mutated genes for cell-line KYSE30 Details
Mutated genes for cell-line NCIH1648 Details
Mutated genes for cell-line NCIH1944 Details
Mutated genes for cell-line SUDHL8 Details
Mutated genes for cell-line ECGI10 Details
Mutated genes for cell-line AU565 Details
Mutated genes for cell-line HCE4 Details
DrugBank drug-targets for investigational drugs Details
Mutated genes for cell-line MDAMB415 Details
Mutated genes for cell-line HUT78 Details
Mutated genes for cell-line HCC515 Details
Mutated genes for cell-line ICC9 Details
Mutated genes for cell-line MRKNU1 Details
Mutated genes for cell-line MM415 Details
Mutated genes for cell-line CGTHW1 Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line TF1 Details
Mutated genes for cell-line SKNBE2 Details
Mutated genes for cell-line CCLFPEDS0008T Details
DrugBank drug-targets for small molecule drugs Details
Mutated genes for cell-line SKBR3 Details
Mutated genes for cell-line ONDA9 Details
Mutated genes for cell-line CROAP3 Details
Mutated genes for cell-line KNS42 Details
Mutated genes for cell-line L540 Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line DL Details
Mutated genes for cell-line MDAMB157 Details
Mutated genes for cell-line MONOMAC6 Details
Mutated genes for cell-line A1207 Details
Mutated genes for cell-line NOZ Details
Mutated genes for cell-line CAMA1 Details
Mutated genes for cell-line SKNO1 Details
Mutated genes for cell-line RERFLCSQ1 Details
Mutated genes for cell-line NALM19 Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line MCAS Details
Mutated genes for cell-line KARPAS422 Details
Mutated genes for cell-line SAT Details
Mutated genes for cell-line PK45H Details
Mutated genes for cell-line KYO1 Details
Mutated genes for cell-line HMVII Details
Mutated genes for cell-line SF295 Details
Mutated genes for cell-line TTC442 Details
Mutated genes for cell-line FEPD Details
Mutated genes for cell-line UMUC6 Details