Available data Protein details
SOS1
c871cbe5-4ed9-4627-a08f-4af58b26ddae
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 11 values.
# Data Value Internal External
HGNC ID 11187 Details Details
HGNC Symbol SOS1 Details -
HGNC Name SOS Ras/Rac guanine nucleotide exchange factor 1 Details -
HGNC Alias GF1 Details -
HGNC Alias GINGF Details -
HGNC Alias HGF Details -
Ensembl ID ENSG00000115904 Details Details
UniProt ID Q07889 Details Details
UniProt Title SOS1_HUMAN Details -
NCBI ID 6654 Details Details
InnateDB ID 47279 Details Details
Interactions
The protein is currently assigned to 121 interactions.
# Interaction Type Links
SOS1 - SNX9 Source Details
AHR - SOS1 Target Details
CAV1 - SOS1 Target Details
SOS1 - GRB2 Source Details
CDK1 - SOS1 Target Details
SOS1 - ABI1 Source Details
MAPK1 - SOS1 Target Details
SOS1 - MAPK1 Source Details
H1-5 - SOS1 Target Details
KPNA1 - SOS1 Target Details
SOS1 - FOXP3 Source Details
HRAS - SOS1 Target Details
BLNK - SOS1 Target Details
SOS1 - GRAP Source Details
PIK3R2 - SOS1 Target Details
PTPN6 - SOS1 Target Details
SOS1 - LAT Source Details
ETS1 - SOS1 Target Details
SOS1 - KPNA6 Source Details
EGFR - SOS1 Target Details
SOS1 - SH3KBP1 Source Details
E2F4 - SOS1 Target Details
MAPK3 - SOS1 Target Details
SOS1 - SPRY2 Source Details
PTPN11 - SOS1 Target Details
ITSN1 - SOS1 Target Details
GRAP - SOS1 Target Details
ABL1 - SOS1 Target Details
GSK3B - SOS1 Target Details
SOS1 - SRC Source Details
SOS1 - PKP4 Source Details
SOS1 - YWHAZ Source Details
FYN - SOS1 Target Details
NCK1 - SOS1 Target Details
ARVCF - SOS1 Target Details
SOS1 - PACSIN3 Source Details
CTNND1 - SOS1 Target Details
CDK2 - SOS1 Target Details
HIF1A - SOS1 Target Details
KRT17 - SOS1 Target Details
PIK3R1 - SOS1 Target Details
SOS1 - ARMC8 Source Details
MUC1 - SOS1 Target Details
AR - SOS1 Target Details
SPRY1 - SOS1 Target Details
SOS1 - SORBS1 Source Details
SOS1 - TNIK Source Details
SRC - SOS1 Target Details
SOS1 - SHC1 Source Details
HCK - SOS1 Target Details
RIT2 - SOS1 Target Details
YBX1 - SOS1 Target Details
SOS1 - SPRY3 Source Details
SOS1 - ARMC7 Source Details
SOS1 - NRAS Source Details
SOS1 - EPS8L1 Source Details
NF2 - SOS1 Target Details
EPS8 - SOS1 Target Details
SOS1 - UBASH3A Source Details
CTNNB1 - SOS1 Target Details
GATA2 - SOS1 Target Details
SOS1 - ITSN2 Source Details
ZAP70 - SOS1 Target Details
BCR - SOS1 Target Details
COPS3 - SOS1 Target Details
SOS1 - EPS8L2 Source Details
SOS1 - SOS1 Source Details
SOS1 - SOS1 Target Details
RET - SOS1 Target Details
SOS1 - FRS2 Source Details
PLCG1 - SOS1 Target Details
SOS1 - KRAS Source Details
SOS1 - PIK3R1 Source Details
MET - SOS1 Target Details
HDLBP - SOS1 Target Details
CSF1R - SOS1 Target Details
SOS1 - COPS3 Source Details
RAP1GDS1 - SOS1 Target Details
SOS1 - SPAG6 Source Details
GRB2 - SOS1 Target Details
CRKL - SOS1 Target Details
KPNA5 - SOS1 Target Details
CRK - SOS1 Target Details
SOS1 - SNX18 Source Details
FGFR1 - SOS1 Target Details
SHC1 - SOS1 Target Details
PTK2B - SOS1 Target Details
SOS1 - NOSTRIN Source Details
SOS1 - MRAS Source Details
CBLB - SOS1 Target Details
SOS1 - TNFRSF1A Source Details
SOS1 - CD2AP Source Details
ESR1 - SOS1 Target Details
RAC1 - SOS1 Target Details
SPRY2 - SOS1 Target Details
CBL - SOS1 Target Details
RPS6KA1 - SOS1 Target Details
SOS1 - RAC1 Source Details
MAPK14 - SOS1 Target Details
CTNND2 - SOS1 Target Details
SOS1 - ARMC1 Source Details
SOS1 - UBC Source Details
SOS1 - GAB1 Source Details
SOS1 - ARMC6 Source Details
EGF - SOS1 Target Details
SOS1 - PACSIN1 Source Details
SOS1 - SPTAN1 Source Details
SOS1 - HRAS Source Details
SOS1 - PKP3 Source Details
LCK - SOS1 Target Details
GAB1 - SOS1 Target Details
ERBB2 - SOS1 Target Details
SOS1 - NCK2 Source Details
SOS1 - ANKAR Source Details
KRAS - SOS1 Target Details
SOS1 - SH3PXD2A Source Details
NEB - SOS1 Target Details
SOS1 - ARMC3 Source Details
SOS1 - SH3BP5 Source Details
PKP2 - SOS1 Target Details
ANXA2 - SOS1 Target Details
Collections
The protein is currently assigned to 52 collections.
# Collection Links
Mutated genes for cell-line SCH Details
Mutated genes for cell-line SKGII Details
Mutated genes for cell-line HEY Details
Mutated genes for cell-line S117 Details
Mutated genes for cell-line U266B1 Details
Mutated genes for cell-line JMSU1 Details
Mutated genes for cell-line HSC4 Details
Mutated genes for cell-line SW872 Details
Mutated genes for cell-line TTC709 Details
Mutated genes for cell-line HMCB Details
Mutated genes for cell-line NCIH1781 Details
Mutated genes for cell-line MKN28 Details
Mutated genes for cell-line MMACSF Details
Mutated genes for cell-line OCILY12 Details
Mutated genes for cell-line CHL1 Details
Mutated genes for cell-line KYSE140 Details
Mutated genes for cell-line CAS1 Details
Mutated genes for cell-line AU565 Details
Mutated genes for cell-line CHP212 Details
Mutated genes for cell-line GSS Details
Mutated genes for cell-line A431 Details
Mutated genes for cell-line M140325 Details
Mutated genes for cell-line RCCMF Details
Mutated genes for cell-line HS839T Details
Mutated genes for cell-line SHI1 Details
Mutated genes for cell-line NB1 Details
Mutated genes for cell-line SJSA1 Details
Mutated genes for cell-line NCIH2023 Details
Mutated genes for cell-line PFSK1 Details
Mutated genes for cell-line AGS Details
Mutated genes for cell-line NP2 Details
Mutated genes for cell-line SKBR3 Details
Mutated genes for cell-line JHOS3 Details
Mutated genes for cell-line PK59 Details
Mutated genes for cell-line KMRC20 Details
Mutated genes for cell-line NCIH1184 Details
Mutated genes for cell-line NCIH1299 Details
Mutated genes for cell-line HOP92 Details
Mutated genes for cell-line A3KAW Details
Mutated genes for cell-line SNU182 Details
Mutated genes for cell-line KGN Details
Mutated genes for cell-line EW24 Details
Mutated genes for cell-line UMUC5 Details
Mutated genes for cell-line G415 Details
Mutated genes for cell-line SNU1079 Details
Mutated genes for cell-line PLCPRF5 Details
Mutated genes for cell-line LXF289 Details
Mutated genes for cell-line A388 Details
Mutated genes for cell-line TKKK Details
Mutated genes for cell-line D392MG Details
Mutated genes for cell-line WM1552C Details
Mutated genes for cell-line SKLU1 Details