Available data
Protein details
DHFR
0388df43-b37b-4a2f-9f62-507c8e4d59d8
Targeting drugs
The protein is currently assigned to 12 targeting drug values.
| # | Data | Value | Internal | External |
|---|---|---|---|---|
| DrugBank Drug ID | DB00205 | Details | Details | |
| DrugBank Drug ID | DB00563 | Details | Details | |
| DrugBank Drug ID | DB00642 | Details | Details | |
| DrugBank Drug ID | DB01131 | Details | Details | |
| DrugBank Drug ID | DB01157 | Details | Details | |
| DrugBank Drug ID | DB06813 | Details | Details | |
| DrugBank Drug Name | Methotrexate | Details | - | |
| DrugBank Drug Name | Pemetrexed | Details | - | |
| DrugBank Drug Name | Pralatrexate | Details | - | |
| DrugBank Drug Name | Proguanil | Details | - | |
| DrugBank Drug Name | Pyrimethamine | Details | - | |
| DrugBank Drug Name | Trimetrexate | Details | - |
Databases
Values
The protein is currently assigned to 20 values.
| # | Data | Value | Internal | External |
|---|---|---|---|---|
| HGNC ID | 2861 | Details | Details | |
| HGNC Symbol | DHFR | Details | - | |
| HGNC Name | dihydrofolate reductase | Details | - | |
| Ensembl ID | ENSG00000228716 | Details | Details | |
| UniProt ID | P00374 | Details | Details | |
| UniProt Title | DYR_HUMAN | Details | - | |
| NCBI ID | 1719 | Details | Details | |
| InnateDB ID | 302986 | Details | Details | |
| DrugBank Drug ID | DB00205 | Details | Details | |
| DrugBank Drug ID | DB00563 | Details | Details | |
| DrugBank Drug ID | DB00642 | Details | Details | |
| DrugBank Drug ID | DB01131 | Details | Details | |
| DrugBank Drug ID | DB01157 | Details | Details | |
| DrugBank Drug ID | DB06813 | Details | Details | |
| DrugBank Drug Name | Methotrexate | Details | - | |
| DrugBank Drug Name | Pemetrexed | Details | - | |
| DrugBank Drug Name | Pralatrexate | Details | - | |
| DrugBank Drug Name | Proguanil | Details | - | |
| DrugBank Drug Name | Pyrimethamine | Details | - | |
| DrugBank Drug Name | Trimetrexate | Details | - |
Interactions
The protein is currently assigned to 19 interactions.
| # | Interaction | Type | Links |
|---|---|---|---|
| DHFR - BCL11A | Source | Details | |
| DHFR - THBS1 | Source | Details | |
| AMFR - DHFR | Target | Details | |
| NFYA - DHFR | Target | Details | |
| DHFR - FKBP1A | Source | Details | |
| DHFR - UBC | Source | Details | |
| DHFR - RXRA | Source | Details | |
| DHFR - HSPD1 | Source | Details | |
| DHFR - TOMM20 | Source | Details | |
| DHFR - BHLHE40 | Source | Details | |
| DHFR - NFYA | Source | Details | |
| DHFR - DHFR | Source | Details | |
| DHFR - DHFR | Target | Details | |
| DHFR - MDM2 | Source | Details | |
| DHFR - E2F1 | Source | Details | |
| TP53 - DHFR | Target | Details | |
| DHFR - GKAP1 | Source | Details | |
| DHFR - TP53 | Source | Details | |
| DHFR - TCF12 | Source | Details |
Collections
The protein is currently assigned to 14 collections.