Available data Protein details
TYK2
1fc8aefd-a8a6-4d12-a5d0-37ef63c0b714
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 9 values.
# Data Value Internal External
HGNC ID 12440 Details Details
HGNC Symbol TYK2 Details -
HGNC Name tyrosine kinase 2 Details -
HGNC Alias JTK1 Details -
Ensembl ID ENSG00000105397 Details Details
UniProt ID P29597 Details Details
UniProt Title TYK2_HUMAN Details -
NCBI ID 7297 Details Details
InnateDB ID 27182 Details Details
Interactions
The protein is currently assigned to 145 interactions.
# Interaction Type Links
TYK2 - FYN Source Details
TYK2 - LYN Source Details
TYK2 - STAT2 Source Details
TYK2 - XRCC5 Source Details
STAT2 - TYK2 Target Details
KLF10 - TYK2 Target Details
CDH8 - TYK2 Target Details
TYK2 - DUSP3 Source Details
TYK2 - DNAAF8 Source Details
TYK2 - ELP2 Source Details
STAT3 - TYK2 Target Details
HSP90AB1 - TYK2 Target Details
SOCS1 - TYK2 Target Details
TYK2 - TNFRSF13B Source Details
JAK3 - TYK2 Target Details
IL15RA - TYK2 Target Details
IL10RA - TYK2 Target Details
TYK2 - PAXBP1 Source Details
TYK2 - IFNAR1 Source Details
TYK2 - JAKMIP1 Source Details
PTPN6 - TYK2 Target Details
PTAFR - TYK2 Target Details
STAT5A - TYK2 Target Details
TYK2 - NLGN3 Source Details
TYK2 - STAT4 Source Details
TYK2 - PRDM5 Source Details
TP53BP1 - TYK2 Target Details
TYK2 - LRRC46 Source Details
TYK2 - VAV1 Source Details
TYK2 - DLGAP4 Source Details
CSF3R - TYK2 Target Details
HCLS1 - TYK2 Target Details
TYK2 - TRAF4 Source Details
TYK2 - PTPN11 Source Details
HNRNPK - TYK2 Target Details
CD79A - TYK2 Target Details
PMEL - TYK2 Target Details
LGALS3BP - TYK2 Target Details
LEPR - TYK2 Target Details
TYK2 - HAVCR2 Source Details
NOS2 - TYK2 Target Details
NFYB - TYK2 Target Details
MPL - TYK2 Target Details
TYK2 - KRTAP6-3 Source Details
TYK2 - MTA1 Source Details
ETS1 - TYK2 Target Details
TYK2 - PRKD2 Source Details
EIF2AK2 - TYK2 Target Details
SMARCC2 - TYK2 Target Details
PTPN11 - TYK2 Target Details
LIFR - TYK2 Target Details
PTPN1 - TYK2 Target Details
SP1 - TYK2 Target Details
DNM2 - TYK2 Target Details
IL4R - TYK2 Target Details
IL1B - TYK2 Target Details
TYK2 - COPS5 Source Details
TYK2 - TNFRSF19 Source Details
TYK2 - JAK3 Source Details
TYK2 - EIF2AK2 Source Details
IL20RB - TYK2 Target Details
EFNB2 - TYK2 Target Details
FOS - TYK2 Target Details
TYK2 - PROSER2 Source Details
STAT5B - TYK2 Target Details
TYK2 - PRMT5 Source Details
TYK2 - LRP8 Source Details
PLAUR - TYK2 Target Details
IFNAR1 - TYK2 Target Details
PRKCA - TYK2 Target Details
TYK2 - GPR156 Source Details
TYK2 - GMNN Source Details
TYK2 - IL13RA1 Source Details
TYK2 - IL6ST Source Details
IL10RB - TYK2 Target Details
CRKL - TYK2 Target Details
PPP1R8 - TYK2 Target Details
GHR - TYK2 Target Details
NFYA - TYK2 Target Details
TYK2 - UBE2L6 Source Details
PDGFRB - TYK2 Target Details
DOK1 - TYK2 Target Details
TYK2 - STAT3 Source Details
VAV1 - TYK2 Target Details
IL22RA1 - TYK2 Target Details
TYK2 - SIVA1 Source Details
TYK2 - RNF13 Source Details
TYK2 - JAK1 Source Details
TYK2 - STAT5B Source Details
TYK2 - ZYX Source Details
TYK2 - TYK2 Source Details
TYK2 - TYK2 Target Details
TYK2 - PTPN6 Source Details
NFKB1 - TYK2 Target Details
IFNB1 - TYK2 Target Details
GATA2 - TYK2 Target Details
TYK2 - CYSRT1 Source Details
IL6ST - TYK2 Target Details
IFNLR1 - TYK2 Target Details
IL20RA - TYK2 Target Details
TYK2 - TMCO3 Source Details
TYK2 - UBE2F Source Details
TYK2 - STAM2 Source Details
TYK2 - KHDRBS2 Source Details
TP53BP2 - TYK2 Target Details
TYK2 - STAT1 Source Details
TYK2 - IRS2 Source Details
NPM1 - TYK2 Target Details
TYK2 - AGR2 Source Details
TYK2 - YWHAE Source Details
KRT31 - TYK2 Target Details
JAK1 - TYK2 Target Details
PTPRC - TYK2 Target Details
COPS5 - TYK2 Target Details
TYK2 - RACK1 Source Details
TYK2 - PTAFR Source Details
FYN - TYK2 Target Details
IFNAR2 - TYK2 Target Details
TYK2 - IL10RA Source Details
TYK2 - IFT43 Source Details
IRF3 - TYK2 Target Details
TYK2 - IL22RA1 Source Details
FHL3 - TYK2 Target Details
TYK2 - STAT5A Source Details
TYK2 - GOLGA6L9 Source Details
TYK2 - UBC Source Details
PPP2R1A - TYK2 Target Details
TYK2 - PLAUR Source Details
IL13RA1 - TYK2 Target Details
TYK2 - IL20RA Source Details
CBL - TYK2 Target Details
LYN - TYK2 Target Details
TYK2 - AKAP8L Source Details
TYK2 - GJA1 Source Details
BCL3 - TYK2 Target Details
IL23R - TYK2 Target Details
STAT1 - TYK2 Target Details
MAS1 - TYK2 Target Details
IL12RB1 - TYK2 Target Details
TYK2 - TERF2IP Source Details
TK1 - TYK2 Target Details
TYK2 - KHDRBS3 Source Details
TYK2 - KRT40 Source Details
SIAH2 - TYK2 Target Details
TYK2 - SOCS1 Source Details
Collections
The protein is currently assigned to 78 collections.
# Collection Links
Mutated genes for cell-line NCIH2141 Details
Mutated genes for cell-line NCIH441 Details
Mutated genes for cell-line COLO684 Details
Mutated genes for cell-line KMBC2 Details
Mutated genes for cell-line COV318 Details
Mutated genes for cell-line DETROIT562 Details
Mutated genes for cell-line CME1 Details
Essential genes for cell-line PaTu_8988S Details
Mutated genes for cell-line MM1S Details
Mutated genes for cell-line COV644 Details
Mutated genes for cell-line WM3211 Details
Mutated genes for cell-line MET2B Details
Mutated genes for cell-line A498 Details
Mutated genes for cell-line SKOV3 Details
Essential genes for cell-line Hs_766T Details
Essential genes for cell-line T-47D Details
Mutated genes for cell-line TALL1 Details
Mutated genes for cell-line LN319 Details
Essential genes for cell-line Capan-2 Details
Mutated genes for cell-line SKMEL30 Details
Mutated genes for cell-line HNT34 Details
Mutated genes for cell-line NCIH250 Details
Mutated genes for cell-line LU135 Details
Mutated genes for cell-line 451LU Details
Mutated genes for cell-line CJM Details
Mutated genes for cell-line GSS Details
Mutated genes for cell-line H2369 Details
Mutated genes for cell-line OVSAHO Details
Mutated genes for cell-line SHI1 Details
Mutated genes for cell-line NCIH2009 Details
Mutated genes for cell-line HCC38 Details
Mutated genes for cell-line F36P Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line HCET Details
Mutated genes for cell-line MCF7 Details
Mutated genes for cell-line OVCAR4 Details
Mutated genes for cell-line NCIH2452 Details
Mutated genes for cell-line M07E Details
Mutated genes for cell-line CHAGOK1 Details
Mutated genes for cell-line D542MG Details
Essential genes for cell-line HCC1187 Details
Essential genes for cell-line MDA-MB-468 Details
Essential genes for cell-line PaTu_8988T Details
Mutated genes for cell-line YD15 Details
Mutated genes for cell-line SKMG1 Details
Mutated genes for cell-line CORL23 Details
Mutated genes for cell-line ONS76 Details
Mutated genes for cell-line BC3C Details
Mutated genes for cell-line HSC2 Details
Mutated genes for cell-line OVMIU Details
Mutated genes for cell-line M00921 Details
Mutated genes for cell-line HKA1 Details
Essential genes for cell-line BT-474 Details
Mutated genes for cell-line HTMMT Details
Mutated genes for cell-line MDAMB231 Details
Mutated genes for cell-line HSC3 Details
Mutated genes for cell-line OMM25 Details
Mutated genes for cell-line MDAMB134VI Details
Mutated genes for cell-line SNU182 Details
Mutated genes for cell-line MZ1B Details
Mutated genes for cell-line NCIH520 Details
Mutated genes for cell-line HARA Details
Mutated genes for cell-line PK8 Details
Mutated genes for cell-line ASH3 Details
Essential genes for cell-line KPL-1 Details
Mutated genes for cell-line JHOS2 Details
Mutated genes for cell-line SW1088 Details
Mutated genes for cell-line CS1 Details
Mutated genes for cell-line HCC1833 Details
Mutated genes for cell-line RXF393 Details
Mutated genes for cell-line TE1 Details
Mutated genes for cell-line TE8 Details
Mutated genes for cell-line SNU489 Details
Mutated genes for cell-line KPL1 Details
Mutated genes for cell-line HS936T Details
Mutated genes for cell-line 647V Details
Mutated genes for cell-line SW1573 Details
Mutated genes for cell-line WM793 Details