Available data Protein details
SMAD4
255f84f1-7711-4ab2-b375-d78cbd2a7051
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 10 values.
# Data Value Internal External
HGNC ID 6770 Details Details
HGNC Symbol SMAD4 Details -
HGNC Name SMAD family member 4 Details -
HGNC Alias DPC4 Details -
HGNC Alias MADH4 Details -
Ensembl ID ENSG00000141646 Details Details
UniProt ID Q13485 Details Details
UniProt Title SMAD4_HUMAN Details -
NCBI ID 4089 Details Details
InnateDB ID 3485 Details Details
Interactions
The protein is currently assigned to 334 interactions.
# Interaction Type Links
SMAD4 - ZIC1 Source Details
FOXO1 - SMAD4 Target Details
AKT1 - SMAD4 Target Details
SMAD4 - FOXO4 Source Details
SMAD4 - GREB1 Source Details
HNF4A - SMAD4 Target Details
SMAD4 - SKI Source Details
EEF1A1 - SMAD4 Target Details
SMAD4 - BCAS3 Source Details
SMAD4 - HMG20A Source Details
SMAD2 - SMAD4 Target Details
SMAD4 - THRSP Source Details
ARNT - SMAD4 Target Details
CD59 - SMAD4 Target Details
IRF3 - SMAD4 Target Details
SMAD4 - COPS5 Source Details
SMAD4 - NCOR1 Source Details
SMAD4 - SMAD7 Source Details
SMAD4 - STK11 Source Details
SMAD4 - SMAD5 Source Details
SMAD4 - RALA Source Details
SMAD4 - KDM6B Source Details
SMAD4 - IL24 Source Details
CREB1 - SMAD4 Target Details
SMAD4 - SMAD9 Source Details
COPS5 - SMAD4 Target Details
SMAD4 - SUMO1 Source Details
SMAD4 - BTRC Source Details
CRYAB - SMAD4 Target Details
SMAD4 - CDKN2B Source Details
SMAD4 - TOB1 Source Details
SMAD4 - FBP2 Source Details
TGIF1 - SMAD4 Target Details
SMAD4 - DCP1A Source Details
SMAD4 - SMURF1 Source Details
SMAD4 - XPO5 Source Details
SMAD4 - DAPK1 Source Details
SMAD4 - PAX8 Source Details
SMAD6 - SMAD4 Target Details
SMAD4 - CYFIP2 Source Details
SMAD4 - ILKAP Source Details
SMAD4 - ZFYVE9 Source Details
SMAD4 - PPP2CB Source Details
GLI2 - SMAD4 Target Details
SMAD4 - EID2 Source Details
SMAD4 - SOX12 Source Details
SMAD4 - CDC14B Source Details
SMAD4 - FOXP3 Source Details
FGFR2 - SMAD4 Target Details
ALK - SMAD4 Target Details
KLF5 - SMAD4 Target Details
SMAD4 - SMAD6 Source Details
SMAD4 - SP1 Source Details
GSK3B - SMAD4 Target Details
NUP153 - SMAD4 Target Details
SMAD4 - TRIM33 Source Details
MELK - SMAD4 Target Details
SMAD4 - MYC Source Details
SMAD4 - AR Source Details
SMAD4 - TFE3 Source Details
SMAD4 - TIAF1 Source Details
SMAD4 - PSMD11 Source Details
UBE2L3 - SMAD4 Target Details
SMAD4 - SERPINE1 Source Details
FN1 - SMAD4 Target Details
CSH2 - SMAD4 Target Details
MAP2K2 - SMAD4 Target Details
SMAD4 - NUP214 Source Details
SMAD3 - SMAD4 Target Details
SMAD4 - PIAS2 Source Details
SMAD1 - SMAD4 Target Details
SMAD4 - NFIA Source Details
SMAD4 - MAPKAPK5 Source Details
SMAD4 - MSANTD3 Source Details
SMAD4 - LYPD3 Source Details
SMAD4 - FHL1 Source Details
SMAD4 - ZMYM2 Source Details
SMAD4 - UBC Source Details
SMAD4 - RFX1 Source Details
SMAD4 - DYRK4 Source Details
IRF7 - SMAD4 Target Details
SMURF2 - SMAD4 Target Details
DACH1 - SMAD4 Target Details
CSNK1E - SMAD4 Target Details
SMAD4 - TGFBR1 Source Details
SMAD4 - SMAD2 Source Details
SMAD4 - GATA2 Source Details
DLX4 - SMAD4 Target Details
ALDOB - SMAD4 Target Details
SMAD4 - YES1 Source Details
SMAD4 - NOTCH4 Source Details
SMURF1 - SMAD4 Target Details
NUP214 - SMAD4 Target Details
SMAD4 - PKP2 Source Details
SMAD4 - NFKBID Source Details
SMAD4 - NF1 Source Details
SMAD4 - UBE2I Source Details
JUNB - SMAD4 Target Details
SMAD4 - RASSF5 Source Details
SMAD4 - PLG Source Details
SMAD4 - VEGFA Source Details
SMAD4 - MAPK8 Source Details
SMAD4 - SNRNP70 Source Details
SMAD4 - CREB1 Source Details
FOS - SMAD4 Target Details
SMAD4 - RPL28 Source Details
SMAD4 - REST Source Details
SMAD4 - STUB1 Source Details
ETV4 - SMAD4 Target Details
CEBPB - SMAD4 Target Details
SMAD4 - S100A14 Source Details
SMAD4 - ARNT Source Details
SMAD4 - WWOX Source Details
ID1 - SMAD4 Target Details
SMAD4 - TM9SF2 Source Details
SMAD4 - ACHE Source Details
ISG15 - SMAD4 Target Details
FANCC - SMAD4 Target Details
SMAD4 - PKP3 Source Details
MAPK3 - SMAD4 Target Details
CTNND1 - SMAD4 Target Details
SKI - SMAD4 Target Details
SMAD4 - HYAL2 Source Details
TRIM33 - SMAD4 Target Details
UBE2I - SMAD4 Target Details
ARAF - SMAD4 Target Details
SMAD4 - MAPK3 Source Details
CDK2 - SMAD4 Target Details
SMAD4 - PSG9 Source Details
SMAD4 - JUN Source Details
SMAD9 - SMAD4 Target Details
ARVCF - SMAD4 Target Details
SMAD4 - PAPPA2 Source Details
SMAD4 - SMAD3 Source Details
SMAD4 - CNKSR1 Source Details
STK11 - SMAD4 Target Details
JUP - SMAD4 Target Details
SMAD4 - SMAD4 Source Details
SMAD4 - SMAD4 Target Details
SMAD4 - HEMGN Source Details
SMAD4 - ZNF189 Source Details
SMAD4 - SHC1 Source Details
ATF2 - SMAD4 Target Details
SMAD4 - PPP3R2 Source Details
EWSR1 - SMAD4 Target Details
ACVR1B - SMAD4 Target Details
SMAD4 - FOS Source Details
DLX1 - SMAD4 Target Details
SMAD4 - PTK2 Source Details
SMAD4 - COL1A1 Source Details
SMAD4 - ZNF423 Source Details
SKP2 - SMAD4 Target Details
HOXA9 - SMAD4 Target Details
SMAD4 - ZBED5 Source Details
HDAC1 - SMAD4 Target Details
SMAD4 - CITED1 Source Details
SMAD4 - SMURF2 Source Details
ETS1 - SMAD4 Target Details
KRT17 - SMAD4 Target Details
GLI1 - SMAD4 Target Details
SMAD4 - ZNF521 Source Details
SMAD4 - PSG2 Source Details
SMAD4 - FOXH1 Source Details
SMAD4 - PIAS4 Source Details
SMAD4 - MYOD1 Source Details
SMAD4 - FHL3 Source Details
DAXX - SMAD4 Target Details
KPNA1 - SMAD4 Target Details
SUMO1 - SMAD4 Target Details
SMAD4 - SKOR2 Source Details
GH1 - SMAD4 Target Details
MAPK1 - SMAD4 Target Details
SMAD4 - SPAG6 Source Details
CEBPA - SMAD4 Target Details
SMAD4 - NR0B2 Source Details
PIAS1 - SMAD4 Target Details
SMAD4 - PIAS3 Source Details
TLE5 - SMAD4 Target Details
SMAD4 - TFDP1 Source Details
SMAD4 - AOPEP Source Details
SMAD4 - SFRP2 Source Details
SMAD4 - BEX1 Source Details
SMAD4 - CTCF Source Details
SMAD4 - TTK Source Details
NKX2-5 - SMAD4 Target Details
SMAD4 - ZBTB7A Source Details
SMAD4 - KLF5 Source Details
SMAD4 - HGS Source Details
SMAD4 - PRKG1 Source Details
SMAD4 - ERBIN Source Details
LCK - SMAD4 Target Details
SMAD4 - HIF1A Source Details
SMAD4 - UHRF2 Source Details
PIAS4 - SMAD4 Target Details
SMAD4 - PAX6 Source Details
SMAD4 - CCDC180 Source Details
WWOX - SMAD4 Target Details
GATA2 - SMAD4 Target Details
SMAD4 - SFRP4 Source Details
JUN - SMAD4 Target Details
SMAD4 - LMO4 Source Details
HIF1A - SMAD4 Target Details
SMAD4 - ANKAR Source Details
FBLN1 - SMAD4 Target Details
SMAD4 - LEF1 Source Details
SMAD4 - MAP3K11 Source Details
SKIL - SMAD4 Target Details
SMAD4 - FHL2 Source Details
SMAD4 - ATF7IP Source Details
SMAD4 - SERPINB5 Source Details
SMAD4 - RPS27A Source Details
USP9X - SMAD4 Target Details
CDKN2B - SMAD4 Target Details
SMAD4 - RBL1 Source Details
SMAD4 - YY1 Source Details
SMAD4 - GNRHR Source Details
SMAD4 - UBB Source Details
FHL2 - SMAD4 Target Details
FHL1 - SMAD4 Target Details
SMAD4 - ARMC3 Source Details
SMAD4 - RAP1GDS1 Source Details
SMAD4 - NRF1 Source Details
CDK5 - SMAD4 Target Details
EIF4E - SMAD4 Target Details
SMAD4 - ARMC8 Source Details
SMAD4 - STX17 Source Details
AR - SMAD4 Target Details
SMAD4 - UBA52 Source Details
SMAD4 - TDG Source Details
SMAD4 - USP9X Source Details
SMAD4 - ISG15 Source Details
CDK7 - SMAD4 Target Details
SMAD4 - PARD3B Source Details
EP300 - SMAD4 Target Details
SMAD4 - MAX Source Details
SMAD4 - ARMC7 Source Details
SMAD4 - USB1 Source Details
SMAD4 - E2F4 Source Details
SMAD4 - NANOG Source Details
SMAD4 - PRKY Source Details
SMAD4 - KPNA6 Source Details
HDLBP - SMAD4 Target Details
SMAD4 - MAPK9 Source Details
SMAD4 - TBX6 Source Details
SMAD4 - PIAS1 Source Details
SMAD4 - SNW1 Source Details
SMAD4 - CDKN1A Source Details
DNAJB2 - SMAD4 Target Details
SMAD4 - TGFB1I1 Source Details
SMAD4 - ARMC6 Source Details
SMAD4 - SNIP1 Source Details
SMAD4 - GPNMB Source Details
SMAD4 - DYRK2 Source Details
SMAD4 - MAPK13 Source Details
HRAS - SMAD4 Target Details
SMAD4 - TGFBRAP1 Source Details
CTNNB1 - SMAD4 Target Details
CSH1 - SMAD4 Target Details
SMAD4 - ITGB7 Source Details
SMAD4 - ATF1 Source Details
EFEMP1 - SMAD4 Target Details
BTRC - SMAD4 Target Details
SMAD4 - SRPK2 Source Details
CDK4 - SMAD4 Target Details
SMAD4 - USP15 Source Details
CITED1 - SMAD4 Target Details
SMAD4 - DCP1B Source Details
ITGB7 - SMAD4 Target Details
NLK - SMAD4 Target Details
HYAL2 - SMAD4 Target Details
SMAD4 - SERPINA1 Source Details
CLK2 - SMAD4 Target Details
SMAD4 - RELA Source Details
CDKN1A - SMAD4 Target Details
MAPK8 - SMAD4 Target Details
SMAD4 - PRPF40A Source Details
SMAD4 - MEF2A Source Details
BAAT - SMAD4 Target Details
SMAD4 - STK11IP Source Details
SMAD4 - PKP4 Source Details
SMAD4 - WWP1 Source Details
UBE2E1 - SMAD4 Target Details
SMAD4 - LAMTOR5 Source Details
SMAD4 - ATF2 Source Details
SMAD4 - LHX4 Source Details
SMAD4 - ZFYVE16 Source Details
SMAD4 - NKX2-5 Source Details
KPNA5 - SMAD4 Target Details
SMAD4 - CREBBP Source Details
SMAD4 - E2F5 Source Details
SMAD4 - NLK Source Details
SMAD4 - HERC5 Source Details
SMAD4 - RNF11 Source Details
SMAD4 - SQSTM1 Source Details
SMAD4 - LRATD2 Source Details
SMAD4 - SPTBN1 Source Details
SMAD5 - SMAD4 Target Details
SMAD4 - SKIL Source Details
SMAD4 - ID1 Source Details
SMAD4 - MOK Source Details
ESR1 - SMAD4 Target Details
SMAD4 - SKP2 Source Details
COL1A1 - SMAD4 Target Details
SMAD4 - WEE1 Source Details
FBXW11 - SMAD4 Target Details
SMAD4 - DKK3 Source Details
SMAD4 - TGFBR2 Source Details
SMAD4 - EP300 Source Details
SMAD4 - ARMC1 Source Details
HOXC8 - SMAD4 Target Details
PDPK1 - SMAD4 Target Details
ACHE - SMAD4 Target Details
FOXO3 - SMAD4 Target Details
SMAD4 - TCTA Source Details
NKX3-2 - SMAD4 Target Details
KPNB1 - SMAD4 Target Details
SNIP1 - SMAD4 Target Details
CREBBP - SMAD4 Target Details
CEBPD - SMAD4 Target Details
SMAD4 - RMND5B Source Details
SMAD4 - ZNF510 Source Details
SMAD4 - ZMIZ1 Source Details
SMAD4 - NELFCD Source Details
SMAD4 - PDPK1 Source Details
SMAD4 - RPS6KA2 Source Details
SMAD4 - NPR2 Source Details
FHL3 - SMAD4 Target Details
CTNND2 - SMAD4 Target Details
SMAD4 - TENM3 Source Details
CAMK2G - SMAD4 Target Details
XPO1 - SMAD4 Target Details
SMAD7 - SMAD4 Target Details
SMAD4 - TSTD2 Source Details
SMAD4 - STK4 Source Details
Collections
The protein is currently assigned to 83 collections.
# Collection Links
Mutated genes for cell-line SKGII Details
Mutated genes for cell-line HUG1N Details
Mutated genes for cell-line KYSE150 Details
Mutated genes for cell-line YAPC Details
Mutated genes for cell-line HT29 Details
Mutated genes for cell-line LB831BLC Details
Mutated genes for cell-line MERO25 Details
Mutated genes for cell-line SW954 Details
Mutated genes for cell-line SNU1105 Details
Mutated genes for cell-line BEN Details
Mutated genes for cell-line ESO26 Details
Mutated genes for cell-line HSC1 Details
Mutated genes for cell-line SNU245 Details
Mutated genes for cell-line CAPAN1 Details
Mutated genes for cell-line HCC1428 Details
Mutated genes for cell-line SW626 Details
Mutated genes for cell-line NCIH2066 Details
Mutated genes for cell-line BOKU Details
Mutated genes for cell-line KYSE450 Details
Mutated genes for cell-line SW1463 Details
Mutated genes for cell-line JHESOAD1 Details
Mutated genes for cell-line SNU308 Details
Mutated genes for cell-line MORCPR Details
Mutated genes for cell-line ASPC1 Details
Mutated genes for cell-line KHYG Details
Mutated genes for cell-line CAL33 Details
Mutated genes for cell-line DOV13 Details
Mutated genes for cell-line PECAPJ34CLONEC12 Details
Mutated genes for cell-line HA7RCC Details
Mutated genes for cell-line WM2664 Details
Mutated genes for cell-line PACADD159 Details
Mutated genes for cell-line P12ICHIKAWA Details
Mutated genes for cell-line KP2 Details
Mutated genes for cell-line CAL27 Details
Mutated genes for cell-line C99 Details
Mutated genes for cell-line NCIH510 Details
Mutated genes for cell-line SNU283 Details
Mutated genes for cell-line SW948 Details
Mutated genes for cell-line AU565 Details
Mutated genes for cell-line H2595 Details
Mutated genes for cell-line BICR31 Details
Mutated genes for cell-line DANG Details
Mutated genes for cell-line PCI38 Details
Mutated genes for cell-line KKU213 Details
Mutated genes for cell-line L33 Details
Mutated genes for cell-line KYM1 Details
Mutated genes for cell-line NB1 Details
Mutated genes for cell-line SNU1196 Details
Mutated genes for cell-line PCI4B Details
Mutated genes for cell-line NCIH2135 Details
Mutated genes for cell-line UMC11 Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line HGC27 Details
Mutated genes for cell-line JHOM2B Details
Mutated genes for cell-line UMUC4 Details
Mutated genes for cell-line OVKATE Details
Mutated genes for cell-line T84 Details
Mutated genes for cell-line LB831EBV Details
Mutated genes for cell-line C80 Details
Mutated genes for cell-line DM3 Details
Mutated genes for cell-line SNU213 Details
Mutated genes for cell-line PANC0203 Details
Mutated genes for cell-line TCCPAN2 Details
Mutated genes for cell-line KP3 Details
Mutated genes for cell-line HSC3 Details
Mutated genes for cell-line PANC0813 Details
Mutated genes for cell-line OV90 Details
Mutated genes for cell-line C2BBE1 Details
Mutated genes for cell-line WM115 Details
Mutated genes for cell-line DJM1 Details
Mutated genes for cell-line MCAS Details
Mutated genes for cell-line 9505BIK Details
Mutated genes for cell-line CACO2 Details
Mutated genes for cell-line SNU869 Details
Mutated genes for cell-line LS123 Details
Mutated genes for cell-line HPAC Details
Mutated genes for cell-line NUDHL1 Details
Mutated genes for cell-line RCM1 Details
Mutated genes for cell-line TE1 Details
Mutated genes for cell-line KURAMOCHI Details
Mutated genes for cell-line MPP89 Details
Mutated genes for cell-line BB30HNC Details
Mutated genes for cell-line SNU738 Details