Available data Protein details
SMAD3
2e51ec7c-de91-4b6c-a067-96380b1f41d6
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 11 values.
# Data Value Internal External
HGNC ID 6769 Details Details
HGNC Symbol SMAD3 Details -
HGNC Name SMAD family member 3 Details -
HGNC Alias HsT17436 Details -
HGNC Alias JV15-2 Details -
HGNC Alias MADH3 Details -
Ensembl ID ENSG00000166949 Details Details
UniProt ID P84022 Details Details
UniProt Title SMAD3_HUMAN Details -
NCBI ID 4088 Details Details
InnateDB ID 18366 Details Details
Interactions
The protein is currently assigned to 520 interactions.
# Interaction Type Links
SMAD3 - EP300 Source Details
SMAD3 - PAPPA Source Details
SMAD3 - ZMIZ1 Source Details
FBXW11 - SMAD3 Target Details
CDK8 - SMAD3 Target Details
SMAD3 - VDR Source Details
KRT10 - SMAD3 Target Details
BPTF - SMAD3 Target Details
SMAD3 - IL36RN Source Details
CSH1 - SMAD3 Target Details
SMAD3 - PITX2 Source Details
SMAD3 - ZNF774 Source Details
DACH1 - SMAD3 Target Details
SMAD3 - PKP2 Source Details
SMAD3 - CCDC33 Source Details
SMAD3 - MYOCD Source Details
SMAD3 - YTHDF2 Source Details
SMAD3 - PRKY Source Details
SMAD3 - ITCH Source Details
SMAD3 - KPNA6 Source Details
SMAD3 - RNF31 Source Details
SMAD3 - ARMC8 Source Details
SMAD3 - COL1A1 Source Details
SMAD3 - RPL3 Source Details
SMAD3 - SRC Source Details
SMAD3 - STRAP Source Details
SMAD3 - RBM4 Source Details
SMAD3 - FAM83G Source Details
SMAD3 - RARA Source Details
NEDD4L - SMAD3 Target Details
SMAD3 - RPS6KA2 Source Details
SMAD3 - FOXO4 Source Details
SMAD3 - SMAD7 Source Details
SMAD3 - E2F4 Source Details
CREBBP - SMAD3 Target Details
BMPR1B - SMAD3 Target Details
SMAD3 - GIT2 Source Details
CBL - SMAD3 Target Details
SMAD3 - AXIN1 Source Details
SMAD3 - SP1 Source Details
ARVCF - SMAD3 Target Details
SMAD3 - PRDM14 Source Details
ISL1 - SMAD3 Target Details
SMAD3 - PPP1R12C Source Details
SMAD3 - PTPN6 Source Details
SMAD3 - STK17B Source Details
SMAD3 - SNRNP70 Source Details
ERBB2 - SMAD3 Target Details
SMAD3 - PIAS2 Source Details
SMAD3 - TCF4 Source Details
SETD2 - SMAD3 Target Details
MAPK8 - SMAD3 Target Details
SMAD3 - ANKAR Source Details
SMAD3 - STX18 Source Details
SMAD3 - DNAJA2 Source Details
SMAD3 - RUNX2 Source Details
SMAD3 - RGCC Source Details
SMAD3 - RIOK2 Source Details
SMAD3 - DYRK1B Source Details
SMAD3 - PAK1 Source Details
SMAD3 - PIAS3 Source Details
SMAD3 - FBXW11 Source Details
SMAD1 - SMAD3 Target Details
SMAD3 - CPSF7 Source Details
SMAD3 - USP15 Source Details
SMAD3 - PAEP Source Details
SMAD3 - SIK3 Source Details
CEBPA - SMAD3 Target Details
SMAD3 - KDM5C Source Details
SMAD3 - PRTN3 Source Details
SMAD3 - PPIL2 Source Details
SMAD3 - MAGI2 Source Details
ERBIN - SMAD3 Target Details
SMAD3 - LEF1 Source Details
SMAD3 - LACRT Source Details
ITGB4 - SMAD3 Target Details
MAPK3 - SMAD3 Target Details
SMAD3 - IRS1 Source Details
GATA3 - SMAD3 Target Details
SMAD3 - TBX3 Source Details
MELK - SMAD3 Target Details
NR4A1 - SMAD3 Target Details
LBP - SMAD3 Target Details
PARP4 - SMAD3 Target Details
SMAD3 - DHX8 Source Details
GMDS - SMAD3 Target Details
SMAD3 - TMED1 Source Details
SMAD3 - CDKN1A Source Details
SMAD3 - TGFB1 Source Details
SMAD3 - PKP3 Source Details
SMAD3 - NEDD9 Source Details
SMAD3 - PRDM16 Source Details
SMAD3 - PIAS4 Source Details
SMAD3 - SKIL Source Details
SMAD3 - YAP1 Source Details
SMAD3 - HEYL Source Details
XRCC6 - SMAD3 Target Details
CTDSPL - SMAD3 Target Details
SMAD3 - PPM1A Source Details
SMAD3 - SLC25A12 Source Details
SMAD3 - VSIR Source Details
SMAD3 - ARMC7 Source Details
SMAD3 - PIN1 Source Details
SMAD3 - SMAD4 Source Details
COL1A1 - SMAD3 Target Details
CEBPB - SMAD3 Target Details
TLE5 - SMAD3 Target Details
SMAD3 - RELA Source Details
SMAD3 - RBBP6 Source Details
SMAD3 - SPAG6 Source Details
SMAD3 - CHD8 Source Details
SMAD3 - CXXC5 Source Details
SMAD3 - TANK Source Details
SMAD3 - TP63 Source Details
SMAD3 - MAPK3 Source Details
SMAD3 - YBX1 Source Details
SMAD3 - KDM2A Source Details
DDX5 - SMAD3 Target Details
PRKCA - SMAD3 Target Details
SMAD3 - ERBIN Source Details
SMAD3 - ARMC1 Source Details
EIF4E - SMAD3 Target Details
SMAD3 - TCP1 Source Details
BRCA1 - SMAD3 Target Details
SMAD3 - SKI Source Details
NOX1 - SMAD3 Target Details
AGL - SMAD3 Target Details
SMAD6 - SMAD3 Target Details
SMAD3 - MEF2C Source Details
HOXC11 - SMAD3 Target Details
SMAD3 - STXBP2 Source Details
SMAD3 - CFDP1 Source Details
PML - SMAD3 Target Details
SMAD3 - MAFK Source Details
CDKN1A - SMAD3 Target Details
SMAD3 - RBPMS Source Details
SMAD3 - CPTP Source Details
APP - SMAD3 Target Details
SMAD3 - BLZF1 Source Details
SMAD3 - RANBP3 Source Details
GATA2 - SMAD3 Target Details
CDC27 - SMAD3 Target Details
SMAD3 - HDAC4 Source Details
SMAD3 - CDKN1B Source Details
CHUK - SMAD3 Target Details
SMAD3 - RPA1 Source Details
SMAD3 - CUL1 Source Details
SMAD3 - KLF5 Source Details
ATF2 - SMAD3 Target Details
SKI - SMAD3 Target Details
SMAD3 - UCHL5 Source Details
GSK3A - SMAD3 Target Details
NR3C1 - SMAD3 Target Details
SMAD3 - TSC2 Source Details
SMAD3 - DAPK1 Source Details
SMAD3 - DNAJB4 Source Details
SMAD3 - TP53 Source Details
SMAD3 - GRIP1 Source Details
SMAD3 - ITGB4 Source Details
WWTR1 - SMAD3 Target Details
SMAD3 - PLG Source Details
PHC2 - SMAD3 Target Details
SMAD3 - KDM6B Source Details
SMAD3 - TCF7L2 Source Details
ATF3 - SMAD3 Target Details
SMAD3 - FOXA1 Source Details
SMAD3 - IL37 Source Details
MAP3K7 - SMAD3 Target Details
KRT17 - SMAD3 Target Details
SMAD3 - GNRHR Source Details
SMAD3 - GAS2L1 Source Details
CDK2 - SMAD3 Target Details
STRAP - SMAD3 Target Details
SMAD2 - SMAD3 Target Details
KLF5 - SMAD3 Target Details
FOXL2 - SMAD3 Target Details
SMAD3 - TFE3 Source Details
CTNND2 - SMAD3 Target Details
AKT3 - SMAD3 Target Details
CFH - SMAD3 Target Details
HP - SMAD3 Target Details
SMAD3 - TRIM62 Source Details
SMAD3 - TGM2 Source Details
PRKACB - SMAD3 Target Details
SMAD3 - ZCCHC14 Source Details
SMAD3 - APMAP Source Details
BRCA2 - SMAD3 Target Details
BMP7 - SMAD3 Target Details
FLNA - SMAD3 Target Details
DYRK1A - SMAD3 Target Details
SMAD3 - SMAD2 Source Details
SMAD3 - ZNF83 Source Details
SMAD3 - GGA1 Source Details
CYP11A1 - SMAD3 Target Details
SMAD3 - IQSEC2 Source Details
SMAD3 - S100A4 Source Details
COL5A1 - SMAD3 Target Details
SMAD3 - NOTCH1 Source Details
SMAD3 - EIF4ENIF1 Source Details
SMAD3 - KMT2B Source Details
SMAD3 - YY1 Source Details
SMAD3 - BTRC Source Details
DHX8 - SMAD3 Target Details
CTNNB1 - SMAD3 Target Details
SMAD3 - MAPK1 Source Details
MAP3K1 - SMAD3 Target Details
KPNB1 - SMAD3 Target Details
SOX11 - SMAD3 Target Details
SMAD3 - UBC Source Details
SMAD3 - CTCF Source Details
SMAD3 - PAX8 Source Details
RNF111 - SMAD3 Target Details
MYD88 - SMAD3 Target Details
SMAD3 - NOTCH4 Source Details
RPL3 - SMAD3 Target Details
SMAD3 - ANAPC10 Source Details
TUBB - SMAD3 Target Details
MAPK1 - SMAD3 Target Details
KAT2B - SMAD3 Target Details
TGFBR2 - SMAD3 Target Details
SMAD3 - NEDD4 Source Details
SMAD3 - SMAD6 Source Details
DVL2 - SMAD3 Target Details
SMAD3 - CSNK1D Source Details
CRX - SMAD3 Target Details
SMAD3 - MCM3AP Source Details
SMAD3 - NF1 Source Details
SMAD3 - SMAD3 Source Details
SMAD3 - SMAD3 Target Details
SMAD4 - SMAD3 Target Details
SMAD3 - SMURF2 Source Details
CEBPD - SMAD3 Target Details
SMAD3 - ZNF263 Source Details
SMAD3 - TGIF1 Source Details
SMAD3 - ATF2 Source Details
PPP2CB - SMAD3 Target Details
SMAD3 - SBK3 Source Details
SMAD3 - ZEB2 Source Details
SMAD3 - ARMC6 Source Details
SMAD3 - FAM90A1 Source Details
SMAD3 - DOCK9 Source Details
SMAD3 - SPTBN1 Source Details
SMAD3 - PCDH1 Source Details
SMAD3 - SQOR Source Details
EP300 - SMAD3 Target Details
FOXM1 - SMAD3 Target Details
SKIL - SMAD3 Target Details
AXIN1 - SMAD3 Target Details
SMAD3 - SECISBP2L Source Details
SMAD3 - STUB1 Source Details
SMAD3 - MIR154 Source Details
SMAD3 - PSMB1 Source Details
PSPC1 - SMAD3 Target Details
SMAD3 - HEY1 Source Details
SMAD3 - TGFBR1 Source Details
SMAD3 - LRCH1 Source Details
TGFA - SMAD3 Target Details
SMAD3 - TEKT4 Source Details
SMAD3 - NFYC Source Details
SMAD3 - U2AF2 Source Details
PTPN6 - SMAD3 Target Details
SMAD3 - SMAD5 Source Details
SMAD3 - UBQLN4 Source Details
RPL4 - SMAD3 Target Details
CDC25A - SMAD3 Target Details
SMAD3 - EID2 Source Details
APOB - SMAD3 Target Details
SMAD3 - E2F5 Source Details
BTK - SMAD3 Target Details
MAPK14 - SMAD3 Target Details
IRF7 - SMAD3 Target Details
FOS - SMAD3 Target Details
SMAD3 - USP7 Source Details
SMAD3 - PPARG Source Details
SMAD3 - RCVRN Source Details
SMAD3 - TFAP2C Source Details
DVL1 - SMAD3 Target Details
NUP153 - SMAD3 Target Details
SMAD3 - NUP153 Source Details
SMAD3 - PLAG1 Source Details
SMAD3 - SMAD1 Source Details
SMAD3 - RANBP9 Source Details
MYC - SMAD3 Target Details
GATA1 - SMAD3 Target Details
SMAD3 - HIPK2 Source Details
SMAD3 - FLI1 Source Details
AR - SMAD3 Target Details
SMAD3 - CAMK1D Source Details
BCAR1 - SMAD3 Target Details
SMAD3 - SS18L1 Source Details
ESR1 - SMAD3 Target Details
CDK4 - SMAD3 Target Details
SMAD3 - PCK2 Source Details
SMAD3 - C1orf116 Source Details
SMAD3 - SOX9 Source Details
SMAD3 - NUP214 Source Details
SMAD3 - APC2 Source Details
SMAD3 - MBD1 Source Details
SMAD3 - DHX16 Source Details
GLI2 - SMAD3 Target Details
SMAD3 - ESR1 Source Details
SMAD3 - FOXH1 Source Details
JUN - SMAD3 Target Details
FOXO3 - SMAD3 Target Details
SMAD3 - SOX11 Source Details
SMAD3 - ZNF251 Source Details
SLC9A3R2 - SMAD3 Target Details
RUNX2 - SMAD3 Target Details
CDK9 - SMAD3 Target Details
CTDSP2 - SMAD3 Target Details
TRIM33 - SMAD3 Target Details
SMAD3 - TAF7 Source Details
SMAD3 - SIN3A Source Details
CHRD - SMAD3 Target Details
SMAD3 - DCAF7 Source Details
AKT1 - SMAD3 Target Details
SMAD3 - NOTCH2 Source Details
GSK3B - SMAD3 Target Details
CXCL12 - SMAD3 Target Details
SMAD3 - NFIC Source Details
SMAD3 - ROCK1 Source Details
SMAD3 - PAX6 Source Details
HIVEP1 - SMAD3 Target Details
CAMK2G - SMAD3 Target Details
SMAD3 - PPP2R1A Source Details
SMAD3 - CDC16 Source Details
SMAD3 - MAPK8 Source Details
ANXA7 - SMAD3 Target Details
SMAD3 - SQSTM1 Source Details
SMAD3 - KANSL1 Source Details
RUNX3 - SMAD3 Target Details
JUP - SMAD3 Target Details
SMAD3 - SETD2 Source Details
EPAS1 - SMAD3 Target Details
SMAD3 - PLAGL1 Source Details
FBLN1 - SMAD3 Target Details
CTDSP1 - SMAD3 Target Details
SMAD3 - DNAJB5 Source Details
EGF - SMAD3 Target Details
CSNK1G2 - SMAD3 Target Details
SMAD3 - FOXP3 Source Details
SMAD3 - NKX2-1 Source Details
SMAD3 - ZEB1 Source Details
SMAD7 - SMAD3 Target Details
CSNK1D - SMAD3 Target Details
SMAD3 - STAT3 Source Details
SMAD3 - TOB1 Source Details
SMAD3 - NOTCH3 Source Details
RANBP3 - SMAD3 Target Details
SMAD3 - MYD88 Source Details
RNF31 - SMAD3 Target Details
EID2 - SMAD3 Target Details
SMAD3 - PML Source Details
PPP2CA - SMAD3 Target Details
SMAD3 - SNW1 Source Details
SMAD3 - SLC6A4 Source Details
PPP1R12C - SMAD3 Target Details
RPS6KA3 - SMAD3 Target Details
SMAD3 - ZBTB3 Source Details
MTMR4 - SMAD3 Target Details
SMAD3 - HDAC5 Source Details
SMAD3 - PKP4 Source Details
SMAD3 - VAV2 Source Details
SMAD3 - RAP1GDS1 Source Details
SMAD3 - WWOX Source Details
CUL1 - SMAD3 Target Details
SMAD3 - ELAC2 Source Details
SMAD3 - TGIF2 Source Details
SMAD3 - TGFB1I1 Source Details
CDK5 - SMAD3 Target Details
ACVR1C - SMAD3 Target Details
SMAD3 - POLR2G Source Details
SMAD3 - ZMYND11 Source Details
ZFYVE9 - SMAD3 Target Details
SMAD3 - SVEP1 Source Details
SMAD3 - CFLAR Source Details
CHD8 - SMAD3 Target Details
SMAD3 - PSMD11 Source Details
SMAD3 - NEK8 Source Details
SMAD3 - HGS Source Details
SMAD3 - NEDD4L Source Details
SMAD3 - ARMC3 Source Details
KAT2A - SMAD3 Target Details
SMAD3 - VEGFA Source Details
SMAD3 - GATA3 Source Details
RUNX1 - SMAD3 Target Details
ETS1 - SMAD3 Target Details
SMAD3 - WDR75 Source Details
SMAD3 - MAP3K7 Source Details
SMAD3 - TSC22D4 Source Details
SMAD3 - AXIN2 Source Details
SMAD3 - RAB11FIP5 Source Details
MECOM - SMAD3 Target Details
SQOR - SMAD3 Target Details
SMAD3 - TGFBR2 Source Details
GRB2 - SMAD3 Target Details
FLI1 - SMAD3 Target Details
SMAD3 - RBL1 Source Details
SMAD3 - PROX1 Source Details
SMAD3 - KAT2B Source Details
SMAD3 - MTF2 Source Details
SMAD3 - ZNF329 Source Details
BTRC - SMAD3 Target Details
SMAD3 - TBC1D10A Source Details
AKT2 - SMAD3 Target Details
SMAD3 - ATXN2L Source Details
SMAD3 - PABPC1 Source Details
SMAD3 - SAP130 Source Details
SMAD3 - GPALPP1 Source Details
SMAD3 - IP6K3 Source Details
SMAD3 - AR Source Details
SMAD3 - FHL3 Source Details
SMAD3 - TF Source Details
SMAD3 - EGR1 Source Details
SMAD3 - SUV39H1 Source Details
SMAD3 - UBL4A Source Details
SMAD3 - PRDM4 Source Details
SMAD3 - SMAD9 Source Details
SMAD3 - FHL1 Source Details
SMAD3 - MEOX2 Source Details
SMAD3 - SMURF1 Source Details
JAK2 - SMAD3 Target Details
HNRNPK - SMAD3 Target Details
SMAD3 - MTMR4 Source Details
SMAD3 - SH2D2A Source Details
IRS1 - SMAD3 Target Details
SMAD3 - SRY Source Details
SMAD3 - NCOA6 Source Details
HDAC1 - SMAD3 Target Details
FHL3 - SMAD3 Target Details
EIF4B - SMAD3 Target Details
SMAD3 - PJA1 Source Details
SMAD3 - RBX1 Source Details
PIAS4 - SMAD3 Target Details
SMAD3 - JPH1 Source Details
SMAD3 - RPLP0 Source Details
SMAD3 - PSPC1 Source Details
SMAD3 - DOCK6 Source Details
ANK3 - SMAD3 Target Details
SMAD3 - FOXO1 Source Details
SMAD3 - EPB41L5 Source Details
SMAD3 - TFDP1 Source Details
SMAD3 - PRCP Source Details
SMAD3 - WWP2 Source Details
SMAD3 - EBI3 Source Details
SMAD3 - FUBP1 Source Details
FHL2 - SMAD3 Target Details
SMAD3 - GMEB1 Source Details
TGFBR1 - SMAD3 Target Details
CSH2 - SMAD3 Target Details
SMAD3 - TRIM33 Source Details
SMAD3 - ZC3H12A Source Details
KPNA1 - SMAD3 Target Details
GDI2 - SMAD3 Target Details
SMAD3 - PARD3B Source Details
SMAD3 - SERTAD1 Source Details
SMAD3 - PITX1 Source Details
SMAD3 - DEDD Source Details
SMAD3 - TRIB3 Source Details
FOXO1 - SMAD3 Target Details
SMAD3 - CREBBP Source Details
DAB2 - SMAD3 Target Details
SMAD3 - ASCC1 Source Details
SMAD3 - MEN1 Source Details
SMAD3 - RNF111 Source Details
SMAD3 - TLR4 Source Details
FHL1 - SMAD3 Target Details
AXL - SMAD3 Target Details
SMAD3 - LEMD3 Source Details
CCNT1 - SMAD3 Target Details
SMAD3 - SERPINE1 Source Details
SMAD3 - CHRD Source Details
LDLRAD4 - SMAD3 Target Details
JUNB - SMAD3 Target Details
PIAS3 - SMAD3 Target Details
SMAD3 - MYC Source Details
BACH1 - SMAD3 Target Details
SMAD3 - MAX Source Details
SMAD3 - BUB3 Source Details
KPNA5 - SMAD3 Target Details
ACVR1B - SMAD3 Target Details
CREB1 - SMAD3 Target Details
SMAD3 - FHL2 Source Details
SMAD3 - JUN Source Details
SMAD3 - PPP2CA Source Details
NUP214 - SMAD3 Target Details
SMAD3 - BRCA1 Source Details
SMAD3 - WWP1 Source Details
UCHL5 - SMAD3 Target Details
HNF4A - SMAD3 Target Details
MAPK10 - SMAD3 Target Details
EGR1 - SMAD3 Target Details
E2F4 - SMAD3 Target Details
SMAD3 - ZBTB16 Source Details
SMAD3 - ST6GALNAC2 Source Details
SMAD3 - NOX4 Source Details
JUND - SMAD3 Target Details
SMAD3 - ZFYVE9 Source Details
SMAD3 - TDP2 Source Details
SMAD3 - SLC39A10 Source Details
MAPK9 - SMAD3 Target Details
CTNND1 - SMAD3 Target Details
SMAD3 - NFIA Source Details
SMAD3 - AATF Source Details
SMAD3 - RPL4 Source Details
TGFB1 - SMAD3 Target Details
PPM1A - SMAD3 Target Details
USP7 - SMAD3 Target Details
SMAD3 - CITED2 Source Details
SMURF1 - SMAD3 Target Details
SMAD3 - CCDC198 Source Details
SMAD3 - NCOA1 Source Details
ACVR1 - SMAD3 Target Details
NODAL - SMAD3 Target Details
SMAD3 - CORO1A Source Details
SMAD3 - SLC9A3R2 Source Details
HIF1A - SMAD3 Target Details
SMAD3 - P3H1 Source Details
SMAD3 - OPA1 Source Details
HSPA4 - SMAD3 Target Details
Collections
The protein is currently assigned to 38 collections.
# Collection Links
Mutated genes for cell-line SNU81 Details
Essential genes for cell-line MCF7 Details
Mutated genes for cell-line CTV1 Details
Mutated genes for cell-line SNU1 Details
Mutated genes for cell-line BICR18 Details
Mutated genes for cell-line SW900 Details
Mutated genes for cell-line A704 Details
Mutated genes for cell-line KASUMI2 Details
Mutated genes for cell-line MDAMB415 Details
Mutated genes for cell-line OS252 Details
Mutated genes for cell-line SNU1040 Details
Mutated genes for cell-line SNU175 Details
Mutated genes for cell-line P30OHK Details
Mutated genes for cell-line CAKI2 Details
Mutated genes for cell-line HEC59 Details
Mutated genes for cell-line LS180 Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line NB12 Details
Mutated genes for cell-line MCF7 Details
Mutated genes for cell-line NP5 Details
Mutated genes for cell-line BICR16 Details
Mutated genes for cell-line SKUT1 Details
Mutated genes for cell-line EFM192A Details
Mutated genes for cell-line NCIH2342 Details
Mutated genes for cell-line HCC2998 Details
Mutated genes for cell-line NUGC4 Details
Mutated genes for cell-line NZOV9 Details
Mutated genes for cell-line DAUDI Details
Mutated genes for cell-line HSOS1 Details
Mutated genes for cell-line SARC9371 Details
Mutated genes for cell-line KARPAS45 Details
Mutated genes for cell-line 2313287 Details
Mutated genes for cell-line CL11 Details
Mutated genes for cell-line HT115 Details
Mutated genes for cell-line JURKAT Details
Mutated genes for cell-line BCPAP Details
Mutated genes for cell-line MESSA Details
Mutated genes for cell-line C75 Details