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Available data Protein details
TOP2A
b1d19090-b4c4-4b82-8254-183027023ef0
Targeting drugs
The protein is currently assigned to 30 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB00276 Details Details
DrugBank Drug ID DB00380 Details Details
DrugBank Drug ID DB00385 Details Details
DrugBank Drug ID DB00444 Details Details
DrugBank Drug ID DB00694 Details Details
DrugBank Drug ID DB00773 Details Details
DrugBank Drug ID DB00997 Details Details
DrugBank Drug ID DB01177 Details Details
DrugBank Drug ID DB01179 Details Details
DrugBank Drug ID DB01204 Details Details
DrugBank Drug ID DB01208 Details Details
DrugBank Drug ID DB04576 Details Details
DrugBank Drug ID DB04967 Details Details
DrugBank Drug ID DB06013 Details Details
DrugBank Drug ID DB09047 Details Details
DrugBank Drug Name Aldoxorubicin Details -
DrugBank Drug Name Amsacrine Details -
DrugBank Drug Name Daunorubicin Details -
DrugBank Drug Name Dexrazoxane Details -
DrugBank Drug Name Doxorubicin Details -
DrugBank Drug Name Etoposide Details -
DrugBank Drug Name Finafloxacin Details -
DrugBank Drug Name Fleroxacin Details -
DrugBank Drug Name Idarubicin Details -
DrugBank Drug Name Lucanthone Details -
DrugBank Drug Name Mitoxantrone Details -
DrugBank Drug Name Podofilox Details -
DrugBank Drug Name Sparfloxacin Details -
DrugBank Drug Name Teniposide Details -
DrugBank Drug Name Valrubicin Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Values
The protein is currently assigned to 39 values.
# Data Value Internal External
HGNC ID 11989 Details Details
HGNC Symbol TOP2A Details -
HGNC Name DNA topoisomerase II alpha Details -
HGNC Alias TOP2 Details -
Ensembl ID ENSG00000131747 Details Details
UniProt ID P11388 Details Details
UniProt Title TOP2A_HUMAN Details -
NCBI ID 7153 Details Details
InnateDB ID 47552 Details Details
DrugBank Drug ID DB00276 Details Details
DrugBank Drug ID DB00380 Details Details
DrugBank Drug ID DB00385 Details Details
DrugBank Drug ID DB00444 Details Details
DrugBank Drug ID DB00694 Details Details
DrugBank Drug ID DB00773 Details Details
DrugBank Drug ID DB00997 Details Details
DrugBank Drug ID DB01177 Details Details
DrugBank Drug ID DB01179 Details Details
DrugBank Drug ID DB01204 Details Details
DrugBank Drug ID DB01208 Details Details
DrugBank Drug ID DB04576 Details Details
DrugBank Drug ID DB04967 Details Details
DrugBank Drug ID DB06013 Details Details
DrugBank Drug ID DB09047 Details Details
DrugBank Drug Name Aldoxorubicin Details -
DrugBank Drug Name Amsacrine Details -
DrugBank Drug Name Daunorubicin Details -
DrugBank Drug Name Dexrazoxane Details -
DrugBank Drug Name Doxorubicin Details -
DrugBank Drug Name Etoposide Details -
DrugBank Drug Name Finafloxacin Details -
DrugBank Drug Name Fleroxacin Details -
DrugBank Drug Name Idarubicin Details -
DrugBank Drug Name Lucanthone Details -
DrugBank Drug Name Mitoxantrone Details -
DrugBank Drug Name Podofilox Details -
DrugBank Drug Name Sparfloxacin Details -
DrugBank Drug Name Teniposide Details -
DrugBank Drug Name Valrubicin Details -
Interactions
The protein is currently assigned to 123 interactions.
# Interaction Type Links
JUN - TOP2A Target Details
SP1 - TOP2A Target Details
FOS - TOP2A Target Details
H2AX - TOP2A Target Details
EIF3E - TOP2A Target Details
TOP2A - VHL Source Details
GLI1 - TOP2A Target Details
RING1 - TOP2A Target Details
TOP2A - PIAS4 Source Details
TOP2A - UHRF1 Source Details
TOP2A - L3MBTL3 Source Details
TOP2A - NOP56 Source Details
TERF2 - TOP2A Target Details
TOP2A - UPF3B Source Details
TOP2A - FAM131B Source Details
TOP2A - CBX1 Source Details
GLI3 - TOP2A Target Details
COX15 - TOP2A Target Details
DAXX - TOP2A Target Details
TOP2A - TFG Source Details
HDAC1 - TOP2A Target Details
TOP2A - FBXW7 Source Details
GLI2 - TOP2A Target Details
TOP2A - RESF1 Source Details
PLK1 - TOP2A Target Details
TOP2A - SUMO1 Source Details
ISG15 - TOP2A Target Details
TOP2A - XRCC5 Source Details
DHX9 - TOP2A Target Details
TOP2A - UBC Source Details
NFYA - TOP2A Target Details
CDK1 - TOP2A Target Details
TOP2A - TP63 Source Details
TOP2A - CDC7 Source Details
DFFB - TOP2A Target Details
TOP2A - VCAM1 Source Details
TOP2A - RBM4B Source Details
SRP72 - TOP2A Target Details
TOP2A - XPO1 Source Details
ATRX - TOP2A Target Details
HDAC2 - TOP2A Target Details
PLK3 - TOP2A Target Details
RB1 - TOP2A Target Details
BRCA1 - TOP2A Target Details
PRKCA - TOP2A Target Details
TOP2A - SUMO4 Source Details
HNRNPU - TOP2A Target Details
PRKDC - TOP2A Target Details
TOP2A - CUL2 Source Details
TOP2A - FBXL13 Source Details
PRKCG - TOP2A Target Details
RRBP1 - TOP2A Target Details
TOP2A - MIR133B Source Details
PRKCB - TOP2A Target Details
PIN1 - TOP2A Target Details
GATA2 - TOP2A Target Details
TOP2A - BRD4 Source Details
SUMO3 - TOP2A Target Details
RPL15 - TOP2A Target Details
TOP2A - TP53 Source Details
TOP2A - H3-4 Source Details
CDC7 - TOP2A Target Details
TOP2A - DDX21 Source Details
MYC - TOP2A Target Details
TOP2A - DHX16 Source Details
SUMO2 - TOP2A Target Details
LMNA - TOP2A Target Details
RNF2 - TOP2A Target Details
CSNK2A1 - TOP2A Target Details
TOP2A - CKAP5 Source Details
TOP2A - MAGT1 Source Details
TOP2A - INTU Source Details
CEBPD - TOP2A Target Details
TOP2A - YY1 Source Details
TOP2A - H2BC9 Source Details
TOP2A - ASB3 Source Details
NR4A1 - TOP2A Target Details
TOP2A - TOP2B Source Details
TOP2A - H3C7 Source Details
MAPK1 - TOP2A Target Details
CTNNB1 - TOP2A Target Details
TOP2A - PRDM14 Source Details
DLST - TOP2A Target Details
TOP2A - CDT1 Source Details
ELOC - TOP2A Target Details
UHRF1 - TOP2A Target Details
PRKCD - TOP2A Target Details
TOP2A - MIR125B2 Source Details
TOP2A - SPIRE2 Source Details
TOP2A - YWHAE Source Details
TOP2A - CTCF Source Details
SRPK1 - TOP2A Target Details
TOP2A - VDAC1 Source Details
TOP2A - CEBPD Source Details
TCF4 - TOP2A Target Details
CDC5L - TOP2A Target Details
HSD3B2 - TOP2A Target Details
RANBP2 - TOP2A Target Details
ETS1 - TOP2A Target Details
IRF3 - TOP2A Target Details
GSK3B - TOP2A Target Details
PBX3 - TOP2A Target Details
THBS3 - TOP2A Target Details
TOP2A - ISG15 Source Details
RAC1 - TOP2A Target Details
MAPK12 - TOP2A Target Details
TOP1 - TOP2A Target Details
TOP2A - COPS5 Source Details
YBX1 - TOP2A Target Details
BMI1 - TOP2A Target Details
TOP2A - CDH19 Source Details
ESR1 - TOP2A Target Details
TOP2A - EIF3I Source Details
TOP2A - TOP2A Source Details
TOP2A - TOP2A Target Details
MAPK3 - TOP2A Target Details
H3-3B - TOP2A Target Details
BLM - TOP2A Target Details
SETMAR - TOP2A Target Details
NFYB - TOP2A Target Details
CSNK2A2 - TOP2A Target Details
TOP2A - UBE2I Source Details
RPA1 - TOP2A Target Details
Collections
The protein is currently assigned to 54 collections.
# Collection Links
Mutated genes for cell-line HUO9 Details
Mutated genes for cell-line NCIH2141 Details
Mutated genes for cell-line HEY Details
Mutated genes for cell-line CI Details
Mutated genes for cell-line SLVL Details
Mutated genes for cell-line NCIH441 Details
Mutated genes for cell-line COLO684 Details
Mutated genes for cell-line HS683 Details
Mutated genes for cell-line INA6 Details
Mutated genes for cell-line NCIH1734 Details
Mutated genes for cell-line KYSE450 Details
Mutated genes for cell-line P31FUJ Details
Mutated genes for cell-line SCLC21H Details
Mutated genes for cell-line SNU840 Details
Mutated genes for cell-line COLO704 Details
Mutated genes for cell-line TGBC1TKB Details
Mutated genes for cell-line TUHR10TKB Details
Mutated genes for cell-line HUCCT1 Details
Mutated genes for cell-line MUGCHOR1 Details
DrugBank drug-targets for investigational drugs Details
Mutated genes for cell-line HEYA8 Details
DrugBank drug-targets for experimental drugs Details
Mutated genes for cell-line NCIH810 Details
Mutated genes for cell-line NCIH1048 Details
Mutated genes for cell-line SCLC22H Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line DB Details
Mutated genes for cell-line CII Details
Mutated genes for cell-line SNU719 Details
DrugBank drug-targets for small molecule drugs Details
Mutated genes for cell-line NB13 Details
DrugBank drug-targets for withdrawn drugs Details
Mutated genes for cell-line CAL148 Details
Mutated genes for cell-line M040416 Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line M980513 Details
Mutated genes for cell-line ABC1 Details
Mutated genes for cell-line T3M4 Details
Mutated genes for cell-line CAOV4 Details
Mutated genes for cell-line ACCS Details
Mutated genes for cell-line ES5 Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line TMK1 Details
Mutated genes for cell-line PK45H Details
Mutated genes for cell-line OVCA420 Details
Mutated genes for cell-line A388 Details
Mutated genes for cell-line COLO668 Details
Mutated genes for cell-line KPNRTBM1 Details
Mutated genes for cell-line KMS12BM Details
Mutated genes for cell-line WSUDLCL2 Details
Mutated genes for cell-line MKN7 Details
Mutated genes for cell-line YSCCC Details
Mutated genes for cell-line HUPT4 Details
Mutated genes for cell-line RAJI Details