Available data Protein details
CHEK1
46c3352e-a65d-479f-b63f-e42d8510d126
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 9 values.
# Data Value Internal External
HGNC ID 1925 Details Details
HGNC Symbol CHEK1 Details -
HGNC Name checkpoint kinase 1 Details -
HGNC Alias CHK1 Details -
Ensembl ID ENSG00000149554 Details Details
UniProt ID O14757 Details Details
UniProt Title CHK1_HUMAN Details -
NCBI ID 1111 Details Details
InnateDB ID 75536 Details Details
Interactions
The protein is currently assigned to 298 interactions.
# Interaction Type Links
CHEK1 - YBX2 Source Details
TERF1 - CHEK1 Target Details
CHEK1 - KPNA1 Source Details
CHEK1 - RBM14 Source Details
CHEK1 - IRAK1 Source Details
CHEK1 - E2F3 Source Details
CHEK1 - TIMELESS Source Details
CHEK1 - SYK Source Details
CHEK1 - SPEN Source Details
CHEK1 - ATR Source Details
CHEK1 - MCM4 Source Details
CHEK1 - TCEAL1 Source Details
FLT3 - CHEK1 Target Details
CHEK1 - RANBP2 Source Details
CHEK1 - DDX24 Source Details
CHEK1 - HNRNPM Source Details
CHEK1 - RRP12 Source Details
CDK2 - CHEK1 Target Details
ETAA1 - CHEK1 Target Details
CLSPN - CHEK1 Target Details
CHEK1 - CEP170B Source Details
CHEK1 - DDX19A Source Details
CHEK1 - AATF Source Details
CHEK1 - PPP1R12A Source Details
CHEK1 - HDGFL2 Source Details
ATR - CHEK1 Target Details
DMC1 - CHEK1 Target Details
CHEK1 - MAD2L1 Source Details
CHEK1 - NFKB1 Source Details
CHEK1 - CDC25C Source Details
CHEK1 - PTTG1 Source Details
CHEK1 - RAD51 Source Details
CHEK1 - PRRC2B Source Details
CHEK1 - PHF2 Source Details
CHEK1 - NEK11 Source Details
CHEK1 - TRIP12 Source Details
CHEK1 - UNC5CL Source Details
CHEK1 - RB1 Source Details
CHEK1 - H3-3A Source Details
CHEK1 - GTF3C1 Source Details
CHEK1 - MAGEA11 Source Details
AKT2 - CHEK1 Target Details
INSR - CHEK1 Target Details
CHEK1 - HLA-DRB5 Source Details
CHEK1 - TNK2 Source Details
CHEK1 - RALY Source Details
CHEK1 - PHF8 Source Details
CHEK1 - XRCC6 Source Details
NBN - CHEK1 Target Details
CHEK1 - UIMC1 Source Details
CDC25C - CHEK1 Target Details
CHEK1 - PLA2G10 Source Details
CHEK1 - PCNA Source Details
CHEK1 - HIVEP1 Source Details
CHEK1 - RIF1 Source Details
CHEK1 - OSBPL11 Source Details
PPM1D - CHEK1 Target Details
GSK3B - CHEK1 Target Details
CHEK1 - ADD3 Source Details
AKT1 - CHEK1 Target Details
CHEK1 - TP53BP1 Source Details
CHEK1 - CHRNA9 Source Details
CHEK1 - BTG3 Source Details
SSB - CHEK1 Target Details
CHEK1 - DDX19B Source Details
CXCL17 - CHEK1 Target Details
CHEK1 - MKI67 Source Details
CHEK1 - STK4 Source Details
PTEN - CHEK1 Target Details
RPS6KA3 - CHEK1 Target Details
CHEK1 - XPO1 Source Details
CHEK1 - SNX11 Source Details
CHEK1 - NAT9 Source Details
CHEK1 - FYTTD1 Source Details
DDB1 - CHEK1 Target Details
CHEK1 - NUP153 Source Details
CHEK1 - TESK2 Source Details
CHEK1 - ACSL3 Source Details
CHEK1 - FANCD2 Source Details
CHEK1 - BRCA2 Source Details
CHEK1 - PIK3R1 Source Details
CHEK1 - PPP2R5D Source Details
CHEK1 - CDK13 Source Details
CHEK1 - FANCE Source Details
CHEK1 - CUL4A Source Details
CHEK1 - PRKCA Source Details
CHEK1 - YWHAB Source Details
APEX1 - CHEK1 Target Details
CHEK1 - ZCCHC17 Source Details
CHEK1 - UBC Source Details
CHEK1 - SRMS Source Details
ATM - CHEK1 Target Details
CHEK1 - ARHGEF2 Source Details
CSNK2B - CHEK1 Target Details
CHEK1 - CUL1 Source Details
CHEK1 - YBX3 Source Details
CHD7 - CHEK1 Target Details
CHEK1 - MAP3K8 Source Details
PPP2CB - CHEK1 Target Details
RRM1 - CHEK1 Target Details
CHEK1 - RASSF1 Source Details
CHEK1 - MYCBP2 Source Details
ADD3 - CHEK1 Target Details
RPS6 - CHEK1 Target Details
CHEK1 - MYBBP1A Source Details
CHEK1 - BAZ1A Source Details
CHEK1 - SENP2 Source Details
CHEK1 - ZNF395 Source Details
CHEK1 - ANKRD12 Source Details
CHEK1 - TNK1 Source Details
APC - CHEK1 Target Details
CHEK1 - EBNA1BP2 Source Details
CHEK1 - RELA Source Details
CHEK2 - CHEK1 Target Details
TP53 - CHEK1 Target Details
CHEK1 - MAPKAPK5 Source Details
CHEK1 - NELFA Source Details
CHEK1 - MAP4 Source Details
CHEK1 - KIFC1 Source Details
CHEK1 - VAV1 Source Details
CHEK1 - SSBP1 Source Details
CHEK1 - ERCC6L Source Details
CDK5RAP3 - CHEK1 Target Details
XIAP - CHEK1 Target Details
CHEK1 - BCL2L14 Source Details
CHEK1 - CTTN Source Details
CHEK1 - NCBP3 Source Details
CHEK1 - SEPTIN7 Source Details
PPP2CA - CHEK1 Target Details
CHEK1 - FEN1 Source Details
CHEK1 - E2F4 Source Details
CHEK1 - YWHAG Source Details
CDK1 - CHEK1 Target Details
BRCA1 - CHEK1 Target Details
CHEK1 - ADD1 Source Details
CHEK1 - CTSE Source Details
CHEK1 - CAMSAP2 Source Details
CHEK1 - CLSPN Source Details
CHEK1 - RAVER1 Source Details
RPS6KA1 - CHEK1 Target Details
CHEK1 - PPME1 Source Details
CHEK1 - CCDC6 Source Details
CHEK1 - TOPBP1 Source Details
CHEK1 - MATR3 Source Details
CHEK1 - SCAF11 Source Details
CHEK1 - AURKB Source Details
CHEK1 - CHEK1 Source Details
CHEK1 - CHEK1 Target Details
CHEK1 - PRKD2 Source Details
CHEK1 - SRC Source Details
CHEK1 - TLK2 Source Details
CHEK1 - MCM3 Source Details
CHEK1 - ILK Source Details
AKT3 - CHEK1 Target Details
CHEK1 - CWC25 Source Details
CHEK1 - SETMAR Source Details
CHEK1 - MCPH1 Source Details
CHEK1 - RBM26 Source Details
CHEK1 - UBA1 Source Details
CHEK1 - SMURF1 Source Details
CHEK1 - POLDIP3 Source Details
CHEK1 - NELL1 Source Details
ADRA2A - CHEK1 Target Details
CHEK1 - TRIM28 Source Details
CHEK1 - GOLGA4 Source Details
CHEK1 - TP73 Source Details
CHEK1 - TICRR Source Details
CHEK1 - DTL Source Details
CHEK1 - MCM5 Source Details
CHEK1 - PRRC2C Source Details
CHEK1 - PRKDC Source Details
CHEK1 - CREBBP Source Details
CHEK1 - HDLBP Source Details
CHEK1 - POP4 Source Details
CHEK1 - DRG2 Source Details
E2F1 - CHEK1 Target Details
CHEK1 - WEE1 Source Details
CHEK1 - RAD23A Source Details
CSNK2A1 - CHEK1 Target Details
CHEK1 - HSP90AB1 Source Details
CHEK1 - SRRM2 Source Details
CHEK1 - FANCL Source Details
CHEK1 - XIAP Source Details
BIRC2 - CHEK1 Target Details
DDR1 - CHEK1 Target Details
CHEK1 - HSP90AA1 Source Details
CHEK1 - FEM1B Source Details
CHEK1 - SIN3A Source Details
CHEK1 - EPRS1 Source Details
PCNA - CHEK1 Target Details
CHEK1 - CHTOP Source Details
H2AX - CHEK1 Target Details
LRIF1 - CHEK1 Target Details
ADD1 - CHEK1 Target Details
CHEK1 - LAMC1 Source Details
CHEK1 - YBX1 Source Details
CHEK1 - UBA2 Source Details
TOPBP1 - CHEK1 Target Details
CHEK1 - PRPF3 Source Details
CHEK1 - TLK1 Source Details
CHEK1 - IDI1 Source Details
CHEK1 - DNAAF11 Source Details
CHEK1 - LATS2 Source Details
TFRC - CHEK1 Target Details
CHEK1 - PLRG1 Source Details
CHEK1 - SNCB Source Details
CHEK1 - CDC7 Source Details
CHEK1 - PROSER2 Source Details
CHEK1 - PIGM Source Details
CHEK1 - UBE2B Source Details
CHEK1 - MDC1 Source Details
CHEK1 - HNRNPA2B1 Source Details
PI3 - CHEK1 Target Details
CHEK1 - MSH2 Source Details
CHEK1 - CHEK2 Source Details
CHEK1 - CDC25B Source Details
CHEK1 - HIPK1 Source Details
CHEK1 - RPL13 Source Details
NF2 - CHEK1 Target Details
CHEK1 - MAP2K1 Source Details
CHEK1 - LDLRAP1 Source Details
CHEK1 - CSNK2A1 Source Details
CHEK1 - MAP2K2 Source Details
CDC25A - CHEK1 Target Details
CHEK1 - MAPT Source Details
CHEK1 - BRCA1 Source Details
CDC25B - CHEK1 Target Details
CHEK1 - CDKN1A Source Details
CHEK1 - MINK1 Source Details
CHEK1 - HES7 Source Details
CHEK1 - BUD13 Source Details
RPA2 - CHEK1 Target Details
CHEK1 - ELAVL1 Source Details
CHEK1 - ZBTB11 Source Details
CHEK1 - E2F6 Source Details
CHEK1 - RBM42 Source Details
CHEK1 - KPNA2 Source Details
CHEK1 - CDK1 Source Details
CHEK1 - ADD2 Source Details
CDK3 - CHEK1 Target Details
CHEK1 - MEN1 Source Details
CHEK1 - MED1 Source Details
ADD2 - CHEK1 Target Details
CHEK1 - OGT Source Details
CHEK1 - CLK3 Source Details
CHEK1 - ZC3HC1 Source Details
CHEK1 - RPS6KA1 Source Details
CHEK1 - HCK Source Details
CHEK1 - TBC1D4 Source Details
CHEK1 - NHS Source Details
RRM2 - CHEK1 Target Details
PIM1 - CHEK1 Target Details
ABL1 - CHEK1 Target Details
BLM - CHEK1 Target Details
CHEK1 - TP53 Source Details
CHEK1 - INF2 Source Details
CHEK1 - ETS1 Source Details
CHEK1 - MED15 Source Details
SMARCA4 - CHEK1 Target Details
CHEK1 - LMO7 Source Details
CHEK1 - ING1 Source Details
CHEK1 - MDM4 Source Details
CHEK1 - LIG1 Source Details
CHEK1 - TFDP1 Source Details
CHEK1 - RACGAP1 Source Details
CHEK1 - WIZ Source Details
CHEK1 - DDB1 Source Details
CHEK1 - CHD7 Source Details
CHEK1 - ERRFI1 Source Details
CHEK1 - CDC25A Source Details
CHEK1 - PLK1 Source Details
CHEK1 - EML3 Source Details
CHEK1 - USP7 Source Details
EGFR - CHEK1 Target Details
CHEK1 - MAPK13 Source Details
CHEK1 - RPL19 Source Details
ATL1 - CHEK1 Target Details
CHEK1 - LMNA Source Details
CHEK1 - MEPE Source Details
CHEK1 - IL13RA2 Source Details
CHEK1 - YWHAZ Source Details
NRAS - CHEK1 Target Details
CHEK1 - CTR9 Source Details
CHEK1 - SLTM Source Details
CHEK1 - ZNF638 Source Details
CHEK1 - BLM Source Details
CHEK1 - NUAK1 Source Details
CHEK1 - POLA1 Source Details
PRKDC - CHEK1 Target Details
MAP3K8 - CHEK1 Target Details
CHEK1 - CSNK2B Source Details
CHEK1 - CAAP1 Source Details
BRCA2 - CHEK1 Target Details
CHEK1 - PRR5 Source Details
RITA1 - CHEK1 Target Details
CHEK1 - H3C1 Source Details
CHEK1 - DNMT1 Source Details
CHEK1 - MSH6 Source Details
Collections
The protein is currently assigned to 69 collections.
# Collection Links
Essential genes for cell-line MDA-MB-436 Details
Essential genes for cell-line SK-OV-3 Details
Essential genes for cell-line OV-1946 Details
Mutated genes for cell-line SKMEL24 Details
Mutated genes for cell-line HCC2157 Details
Mutated genes for cell-line TE4 Details
Essential genes for cell-line MDA-MB-361 Details
Mutated genes for cell-line NB4 Details
Essential genes for cell-line OVCA1369_TR Details
Essential genes for cell-line Hs_578T Details
Mutated genes for cell-line GP2D Details
Essential genes for cell-line MCF7 Details
Essential genes for cell-line CFPAC-1 Details
Mutated genes for cell-line BB30PBL Details
Mutated genes for cell-line SNU520 Details
Essential genes for cell-line Hs_766T Details
Essential genes for cell-line HCC1419 Details
Essential genes for cell-line Panc_03 Details
Essential genes for cell-line Capan-2 Details
Essential genes for cell-line HCC1500 Details
Essential genes for cell-line A2780_CIS Details
Essential genes for cell-line CAMA-1 Details
Essential genes for cell-line SK-BR-3 Details
Mutated genes for cell-line GSU Details
Essential genes for cell-line HCC1954 Details
Essential genes for cell-line OVCAR-3 Details
Essential genes for cell-line CAL-51 Details
Mutated genes for cell-line LS411N Details
Mutated genes for cell-line HEC108 Details
Mutated genes for cell-line MM127 Details
Mutated genes for cell-line REH Details
Essential genes for cell-line HCC1806 Details
Essential genes for cell-line PL45 Details
Mutated genes for cell-line UMUC10 Details
Essential genes for cell-line PANC-1 Details
Mutated genes for cell-line SNU1040 Details
Mutated genes for cell-line SNU175 Details
Essential genes for cell-line OV-90 Details
Mutated genes for cell-line HCC2157BL Details
Essential genes for cell-line HCC1428 Details
Essential genes for cell-line MIA_PaCa-2 Details
Essential genes for cell-line BT-20 Details
Essential genes for cell-line AsPC-1 Details
Mutated genes for cell-line HEC251 Details
Essential genes for cell-line HPDE Details
Mutated genes for cell-line PATU8988S Details
Essential genes for cell-line MDA-MB-157 Details
Mutated genes for cell-line KHM1B Details
Essential genes for cell-line EFM-19 Details
Essential genes for cell-line HCC1187 Details
Essential genes for cell-line MDA-MB-468 Details
Essential genes for cell-line PaTu_8988T Details
Essential genes for cell-line A2780 Details
Essential genes for cell-line HCC1143 Details
Essential genes for cell-line HCC38 Details
Essential genes for cell-line TOV-3133G Details
Mutated genes for cell-line DMS79 Details
Mutated genes for cell-line NZOV9 Details
Essential genes for cell-line TOV-1946 Details
Mutated genes for cell-line CAL51 Details
Essential genes for cell-line KPL-1 Details
Mutated genes for cell-line DMS273 Details
Essential genes for cell-line ZR-75-1 Details
Mutated genes for cell-line JHUEM7 Details
Mutated genes for cell-line DND41 Details
Mutated genes for cell-line PANC1005 Details
Mutated genes for cell-line GP5D Details
Essential genes for cell-line OVCA5 Details
Mutated genes for cell-line BB30HNC Details