Available data Protein details
ROCK1
c9a441f5-1721-4ce4-bdd3-7bd99bfd62fa
Targeting drugs
The protein is currently assigned to 2 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB13931 Details Details
DrugBank Drug Name Netarsudil Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Values
The protein is currently assigned to 11 values.
# Data Value Internal External
HGNC ID 10251 Details Details
HGNC Symbol ROCK1 Details -
HGNC Name Rho associated coiled-coil containing protein kinase 1 Details -
HGNC Alias p160ROCK Details -
Ensembl ID ENSG00000067900 Details Details
UniProt ID Q13464 Details Details
UniProt Title ROCK1_HUMAN Details -
NCBI ID 6093 Details Details
InnateDB ID 1371 Details Details
DrugBank Drug ID DB13931 Details Details
DrugBank Drug Name Netarsudil Details -
Interactions
The protein is currently assigned to 162 interactions.
# Interaction Type Links
ROCK1 - MAPK8IP3 Source Details
ROCK1 - PPP1R12B Source Details
CDK2 - ROCK1 Target Details
ROCK1 - LIMK2 Source Details
ROCK1 - CDKN1B Source Details
MAGEB4 - ROCK1 Target Details
PTK2 - ROCK1 Target Details
ROCK1 - KCNK3 Source Details
ROCK1 - DAPK3 Source Details
RHOA - ROCK1 Target Details
ROCK1 - GPAA1 Source Details
ROCK1 - ANKAR Source Details
ROCK1 - SCRIB Source Details
ROCK1 - ARHGAP19 Source Details
ROCK1 - ROCK1 Source Details
ROCK1 - ROCK1 Target Details
ROCK1 - ARMC8 Source Details
ROCK1 - MYL2 Source Details
NCL - ROCK1 Target Details
ROCK1 - GPATCH4 Source Details
ROCK1 - MYH10 Source Details
ROCK1 - PTEN Source Details
CTNND1 - ROCK1 Target Details
MIR146A - ROCK1 Target Details
ROCK1 - IL20RA Source Details
CDC25A - ROCK1 Target Details
MSN - ROCK1 Target Details
ROCK1 - SNAP29 Source Details
ROCK1 - EZR Source Details
ROCK1 - KPNA6 Source Details
CASP3 - ROCK1 Target Details
ROCK1 - SH3GL2 Source Details
ROCK1 - RND3 Source Details
ROCK1 - SMARCC1 Source Details
ROCK1 - VIM Source Details
ROCK1 - SIRT6 Source Details
PPP1R12A - ROCK1 Target Details
PFN1 - ROCK1 Target Details
ADD2 - ROCK1 Target Details
DPYSL2 - ROCK1 Target Details
ROCK1 - LIMK1 Source Details
SMAD2 - ROCK1 Target Details
ROCK1 - CASP3 Source Details
DAPK3 - ROCK1 Target Details
ROCK1 - CDC25A Source Details
AR - ROCK1 Target Details
ROCK1 - GAS2L3 Source Details
ROCK1 - MSN Source Details
ROCK1 - MYL12A Source Details
ROCK1 - DPYSL2 Source Details
ROCK1 - ITSN2 Source Details
CTNNB1 - ROCK1 Target Details
NEB - ROCK1 Target Details
ROCK1 - ARMC6 Source Details
MBP - ROCK1 Target Details
ROCK1 - XRCC5 Source Details
RAP1GDS1 - ROCK1 Target Details
RND3 - ROCK1 Target Details
ROCK1 - RHOA Source Details
ROCK1 - IFT88 Source Details
RDX - ROCK1 Target Details
ROCK1 - PPP1R12A Source Details
CD44 - ROCK1 Target Details
ROCK1 - STX18 Source Details
ROCK1 - TP53 Source Details
RAD51 - ROCK1 Target Details
ROCK1 - SOX9 Source Details
MYBPH - ROCK1 Target Details
MARCKS - ROCK1 Target Details
ROCK1 - H3C1 Source Details
MAPK1 - ROCK1 Target Details
ROCK1 - SPAG6 Source Details
SHROOM2 - ROCK1 Target Details
ROCK1 - CFTR Source Details
ROCK1 - POLR3C Source Details
ROCK1 - SSR3 Source Details
ROCK1 - PKP3 Source Details
KPNA5 - ROCK1 Target Details
ROCK1 - FAM124A Source Details
ROCK1 - YY1 Source Details
ROCK1 - RETREG3 Source Details
ROCK1 - ADD1 Source Details
EGR1 - ROCK1 Target Details
VIM - ROCK1 Target Details
DVL1 - ROCK1 Target Details
ETS1 - ROCK1 Target Details
ROCK1 - TSC2 Source Details
ROCK1 - ARMC3 Source Details
ROCK1 - ARMC7 Source Details
SMAD3 - ROCK1 Target Details
ROCK1 - PSRC1 Source Details
ROCK1 - PTK2 Source Details
ROCK1 - FRMD5 Source Details
GFAP - ROCK1 Target Details
ADD1 - ROCK1 Target Details
ROCK1 - DOCK5 Source Details
PPP1R12B - ROCK1 Target Details
PFN2 - ROCK1 Target Details
ROCK1 - PKP4 Source Details
ROCK1 - ENY2 Source Details
ROCK1 - IRS1 Source Details
ROCK1 - ROCK2 Source Details
ROCK1 - MAPK1 Source Details
ROCK1 - PRMT5 Source Details
ROCK1 - MYLK Source Details
CFL1 - ROCK1 Target Details
ROCK1 - MPRIP Source Details
ROCK1 - MAPK8 Source Details
DES - ROCK1 Target Details
KRT17 - ROCK1 Target Details
ROCK1 - SLC9A1 Source Details
ROCK1 - FOXP3 Source Details
ROCK1 - ATP6V0A2 Source Details
ROCK1 - CEPT1 Source Details
ROCK1 - MYC Source Details
ROCK1 - NEIL3 Source Details
CTNND2 - ROCK1 Target Details
ROCK1 - SMARCA4 Source Details
ROCK1 - CASKIN1 Source Details
ROCK1 - RDX Source Details
PKP2 - ROCK1 Target Details
LIMK2 - ROCK1 Target Details
ROCK1 - GFAP Source Details
ROCK1 - BECN1 Source Details
ROCK1 - KCNH2 Source Details
ROCK1 - ARHGAP35 Source Details
ROCK1 - DNM1L Source Details
ROCK1 - DYNC1LI1 Source Details
ROCK1 - DOCK6 Source Details
PRKCI - ROCK1 Target Details
ARVCF - ROCK1 Target Details
ROCK1 - ARMC1 Source Details
HSP90AB1 - ROCK1 Target Details
PTEN - ROCK1 Target Details
ROCK1 - MYL12B Source Details
ROCK1 - PIP5K1C Source Details
ROCK1 - GAB1 Source Details
ROCK1 - TRIM15 Source Details
ROCK1 - TSG101 Source Details
ROCK1 - UBE2M Source Details
ROCK1 - CFAP206 Source Details
ROCK1 - FHOD1 Source Details
ROCK2 - ROCK1 Target Details
ROCK1 - MAP2K4 Source Details
ROCK1 - MAPT Source Details
ROCK1 - MARCKS Source Details
LIMK1 - ROCK1 Target Details
RAC1 - ROCK1 Target Details
GAB1 - ROCK1 Target Details
ROCK1 - ARHGAP24 Source Details
ROCK1 - SLC39A10 Source Details
KPNA1 - ROCK1 Target Details
ROCK1 - PRDM14 Source Details
ROCK1 - DES Source Details
HSPA1B - ROCK1 Target Details
EZR - ROCK1 Target Details
LMO2 - ROCK1 Target Details
ROCK1 - FBH1 Source Details
ROCK1 - PFN1 Source Details
ROCK1 - ZNF263 Source Details
ROCK1 - MYL9 Source Details
ARHGAP35 - ROCK1 Target Details
Collections
The protein is currently assigned to 120 collections.
# Collection Links
Mutated genes for cell-line HCC2450 Details
Essential genes for cell-line HPAC Details
Mutated genes for cell-line SNUC4 Details
Essential genes for cell-line OV-1946 Details
Mutated genes for cell-line SUDHL10 Details
Mutated genes for cell-line SW48 Details
Mutated genes for cell-line CHSA0011 Details
Mutated genes for cell-line KG1C Details
Mutated genes for cell-line OAW42 Details
Mutated genes for cell-line SNU1077 Details
Mutated genes for cell-line KPNYS Details
Mutated genes for cell-line NCIH748 Details
Mutated genes for cell-line NCIH522 Details
Mutated genes for cell-line RCCER Details
Mutated genes for cell-line CORL95 Details
Mutated genes for cell-line BHT101 Details
Mutated genes for cell-line F5 Details
Mutated genes for cell-line NCIH524 Details
Mutated genes for cell-line CCK81 Details
Mutated genes for cell-line SUDHL5 Details
Mutated genes for cell-line OVTOKO Details
Mutated genes for cell-line KYSE450 Details
Mutated genes for cell-line G292CLONEA141B1 Details
Mutated genes for cell-line GP2D Details
Mutated genes for cell-line BT16 Details
Mutated genes for cell-line P31FUJ Details
Mutated genes for cell-line NCIH1437 Details
Mutated genes for cell-line LN18 Details
Mutated genes for cell-line MSDASH1 Details
Mutated genes for cell-line EW1 Details
Essential genes for cell-line T-47D Details
Mutated genes for cell-line BICR18 Details
Mutated genes for cell-line HA7RCC Details
Mutated genes for cell-line CALU1 Details
Mutated genes for cell-line SLR23 Details
Mutated genes for cell-line HUH28 Details
Mutated genes for cell-line TC138 Details
Mutated genes for cell-line HCC1588 Details
Mutated genes for cell-line IGROV1 Details
Mutated genes for cell-line FARAGE Details
Mutated genes for cell-line K5 Details
Mutated genes for cell-line HEC108 Details
Mutated genes for cell-line DU145 Details
Mutated genes for cell-line ES8 Details
Mutated genes for cell-line EN Details
Mutated genes for cell-line L1236 Details
Mutated genes for cell-line SNU1040 Details
Mutated genes for cell-line SNU175 Details
Mutated genes for cell-line FUOV1 Details
Mutated genes for cell-line ESS1 Details
Mutated genes for cell-line PC9 Details
Mutated genes for cell-line CW2 Details
Mutated genes for cell-line SNUC2A Details
Mutated genes for cell-line HEC59 Details
Mutated genes for cell-line HRT18 Details
Mutated genes for cell-line HEC251 Details
Mutated genes for cell-line CMLT1 Details
Mutated genes for cell-line DMS153 Details
Mutated genes for cell-line HEC265 Details
Mutated genes for cell-line RCCJF Details
DrugBank drug-targets for small molecule drugs Details
Mutated genes for cell-line LC2AD Details
Mutated genes for cell-line MDAPCA2B Details
Mutated genes for cell-line M059J Details
Mutated genes for cell-line HPBALL Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line SNU1544 Details
Mutated genes for cell-line RPMI8866 Details
Mutated genes for cell-line MDAMB361 Details
Mutated genes for cell-line RKO Details
Mutated genes for cell-line SNU1041 Details
Mutated genes for cell-line MFE319 Details
Mutated genes for cell-line SNU503 Details
Mutated genes for cell-line HHUA Details
Mutated genes for cell-line WM4235 Details
Mutated genes for cell-line HCT15 Details
Mutated genes for cell-line MHHES1 Details
Mutated genes for cell-line HCC2998 Details
Mutated genes for cell-line HSC5 Details
Mutated genes for cell-line ABC1 Details
Mutated genes for cell-line KNS60 Details
Mutated genes for cell-line CAL78 Details
Mutated genes for cell-line LS513 Details
Mutated genes for cell-line DAUDI Details
Mutated genes for cell-line HS172T Details
Mutated genes for cell-line SARC9371 Details
Mutated genes for cell-line SCMCRM2 Details
Mutated genes for cell-line A3KAW Details
Mutated genes for cell-line KARPAS45 Details
Mutated genes for cell-line MKN1 Details
Mutated genes for cell-line NCIBL2087 Details
Mutated genes for cell-line NCIH211 Details
Mutated genes for cell-line 2313287 Details
Mutated genes for cell-line PANC0813 Details
Mutated genes for cell-line NOMO1 Details
Mutated genes for cell-line MOLT16 Details
Mutated genes for cell-line HT115 Details
Mutated genes for cell-line HA7EBV Details
Mutated genes for cell-line OAW28 Details
Mutated genes for cell-line OSC20 Details
Mutated genes for cell-line PCM6 Details
Mutated genes for cell-line SLR24 Details
Mutated genes for cell-line CAL72 Details
Mutated genes for cell-line NCIH1666 Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line MM383 Details
Mutated genes for cell-line HCC1438 Details
Mutated genes for cell-line NUGC2 Details
Mutated genes for cell-line SKMES1 Details
Mutated genes for cell-line JHUEM7 Details
Mutated genes for cell-line CA922 Details
Mutated genes for cell-line SNUC2B Details
Mutated genes for cell-line GP5D Details
Mutated genes for cell-line SNU407 Details
Mutated genes for cell-line NUDUL1 Details
Mutated genes for cell-line HMEL Details
Mutated genes for cell-line M059K Details
Mutated genes for cell-line MC116 Details
Mutated genes for cell-line NKM1 Details
Mutated genes for cell-line NCIH1876 Details