Available data Protein details
RAF1
dc7534e3-3e59-470c-9265-427fd5cb60a1
Targeting drugs
The protein is currently assigned to 6 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB00398 Details Details
DrugBank Drug ID DB08896 Details Details
DrugBank Drug ID DB08912 Details Details
DrugBank Drug Name Dabrafenib Details -
DrugBank Drug Name Regorafenib Details -
DrugBank Drug Name Sorafenib Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Interactions
The protein is currently assigned to 347 interactions.
# Interaction Type Links
PRKCE - RAF1 Target Details
RAF1 - CDC25B Source Details
RAF1 - PEBP1 Source Details
RAF1 - VAV1 Source Details
YRDC - RAF1 Target Details
LTK - RAF1 Target Details
ETS1 - RAF1 Target Details
BIRC2 - RAF1 Target Details
BCR - RAF1 Target Details
PPP5C - RAF1 Target Details
EGFR - RAF1 Target Details
RAF1 - NPLOC4 Source Details
PRKCZ - RAF1 Target Details
RAF1 - MAP3K1 Source Details
HCLS1 - RAF1 Target Details
BAG2 - RAF1 Target Details
PHB - RAF1 Target Details
PPP2R2A - RAF1 Target Details
SPRY4 - RAF1 Target Details
RAF1 - CCT3 Source Details
ATF2 - RAF1 Target Details
RAF1 - CBLC Source Details
ERBB2 - RAF1 Target Details
RAF1 - IRS4 Source Details
MAP2K2 - RAF1 Target Details
SHOC2 - RAF1 Target Details
RAF1 - AKT1 Source Details
EIF2AK2 - RAF1 Target Details
RAF1 - INTS10 Source Details
PRL - RAF1 Target Details
XIAP - RAF1 Target Details
RAF1 - PPP1CC Source Details
PHKA2 - RAF1 Target Details
GRM1 - RAF1 Target Details
KNG1 - RAF1 Target Details
CRKL - RAF1 Target Details
SPP1 - RAF1 Target Details
JAK2 - RAF1 Target Details
HSPD1 - RAF1 Target Details
PPP1R8 - RAF1 Target Details
RAF1 - MAP2K2 Source Details
RAF1 - CACYBP Source Details
PPP2R5D - RAF1 Target Details
ARAF - RAF1 Target Details
AKT2 - RAF1 Target Details
RAF1 - BAG1 Source Details
RAF1 - MAP3K5 Source Details
SORBS1 - RAF1 Target Details
AR - RAF1 Target Details
RAF1 - YWHAG Source Details
RAF1 - MAP2K1 Source Details
RAF1 - CNKSR2 Source Details
PRKAR1A - RAF1 Target Details
RAF1 - AGTR1 Source Details
AGTR1 - RAF1 Target Details
RAF1 - YWHAZ Source Details
IL4 - RAF1 Target Details
RAF1 - PRKAG3 Source Details
HSPA8 - RAF1 Target Details
RAF1 - ZYX Source Details
RAF1 - ARRB2 Source Details
NR3C1 - RAF1 Target Details
YWHAB - RAF1 Target Details
RAF1 - NRAS Source Details
RAF1 - MRC2 Source Details
CSK - RAF1 Target Details
RAF1 - MYC Source Details
CDKN1A - RAF1 Target Details
RAF1 - SRXN1 Source Details
RAF1 - RAP2A Source Details
RAF1 - STK3 Source Details
SPG7 - RAF1 Target Details
RAF1 - OPRM1 Source Details
RAF1 - KSR2 Source Details
BAD - RAF1 Target Details
PLK1 - RAF1 Target Details
HSPA4 - RAF1 Target Details
PDGFRB - RAF1 Target Details
BAG1 - RAF1 Target Details
RAF1 - BECN1 Source Details
RRAS - RAF1 Target Details
RAF1 - RB1 Source Details
CDC25A - RAF1 Target Details
RAF1 - FYCO1 Source Details
DLX3 - RAF1 Target Details
RAF1 - WDR83 Source Details
RAF1 - CAMK2A Source Details
RAF1 - MLF2 Source Details
IFNG - RAF1 Target Details
PRKCB - RAF1 Target Details
BRAF - RAF1 Target Details
PPP1CB - RAF1 Target Details
PPP1CA - RAF1 Target Details
HLCS - RAF1 Target Details
RAF1 - LATS1 Source Details
RAF1 - UBC Source Details
PDGFRA - RAF1 Target Details
CAMK2A - RAF1 Target Details
PRKG1 - RAF1 Target Details
RAF1 - ARAF Source Details
STK3 - RAF1 Target Details
PTPN1 - RAF1 Target Details
ARNT - RAF1 Target Details
RAF1 - IL2RB Source Details
RAF1 - CASZ1 Source Details
RAF1 - PEBP4 Source Details
RAF1 - TEAD2 Source Details
MAP2K5 - RAF1 Target Details
RAF1 - YWHAE Source Details
EGF - RAF1 Target Details
RAF1 - SARS1 Source Details
MAPK8 - RAF1 Target Details
HRAS - RAF1 Target Details
RHEB - RAF1 Target Details
RAF1 - RRAS Source Details
RAF1 - AARSD1 Source Details
NF1 - RAF1 Target Details
RAF1 - RELA Source Details
MAP2K1 - RAF1 Target Details
MET - RAF1 Target Details
KRT8 - RAF1 Target Details
MAP3K1 - RAF1 Target Details
RAF1 - TERT Source Details
FGF2 - RAF1 Target Details
RCAN1 - RAF1 Target Details
RAF1 - TSC22D3 Source Details
KSR2 - RAF1 Target Details
SRC - RAF1 Target Details
HCK - RAF1 Target Details
YWHAZ - RAF1 Target Details
EEF1A2 - RAF1 Target Details
RAF1 - MAPK8IP3 Source Details
RAF1 - PAK1 Source Details
RAF1 - STK4 Source Details
MRAS - RAF1 Target Details
RAF1 - STIP1 Source Details
RAF1 - DCAF8 Source Details
RAF1 - TMEM70 Source Details
CDK6 - RAF1 Target Details
RAF1 - RAP1A Source Details
RAF1 - RANBP9 Source Details
RAF1 - KRAS Source Details
RAF1 - MPRIP Source Details
KRT19 - RAF1 Target Details
SFN - RAF1 Target Details
RAF1 - HSP90AA1 Source Details
RAF1 - HSPA4 Source Details
RAF1 - SGK1 Source Details
BCL2L1 - RAF1 Target Details
RAF1 - XIAP Source Details
RAF1 - PDLIM2 Source Details
RAF1 - YY1 Source Details
LATS1 - RAF1 Target Details
HSP90AA1 - RAF1 Target Details
RAF1 - TIMM23 Source Details
NF2 - RAF1 Target Details
RAF1 - CSDE1 Source Details
HSPA5 - RAF1 Target Details
EPHA2 - RAF1 Target Details
CD44 - RAF1 Target Details
RAF1 - PRPF6 Source Details
RRAS2 - RAF1 Target Details
ILK - RAF1 Target Details
LRPAP1 - RAF1 Target Details
RAF1 - COPS7A Source Details
PRKCA - RAF1 Target Details
PPP2R1A - RAF1 Target Details
CERK - RAF1 Target Details
RHOA - RAF1 Target Details
BIRC3 - RAF1 Target Details
EEF1A1 - RAF1 Target Details
MAPK7 - RAF1 Target Details
MIR143 - RAF1 Target Details
PKM - RAF1 Target Details
LGI1 - RAF1 Target Details
RAF1 - COPS3 Source Details
PHLPP1 - RAF1 Target Details
CD209 - RAF1 Target Details
RAF1 - NEDD4L Source Details
PSMD2 - RAF1 Target Details
EPO - RAF1 Target Details
PIN1 - RAF1 Target Details
HACD1 - RAF1 Target Details
MAPK3 - RAF1 Target Details
RAF1 - KEAP1 Source Details
RAF1 - SCNN1B Source Details
RAF1 - SRC Source Details
CDKN2C - RAF1 Target Details
RAF1 - CDK10 Source Details
RAF1 - EEF1A1 Source Details
PURA - RAF1 Target Details
MYC - RAF1 Target Details
RAF1 - YWHAQ Source Details
RAF1 - TIMM50 Source Details
CDKN2B - RAF1 Target Details
PPP2CB - RAF1 Target Details
RAF1 - CFLAR Source Details
RASSF1 - RAF1 Target Details
RAF1 - BAG2 Source Details
RAF1 - TBXA2R Source Details
PPP2CA - RAF1 Target Details
RAF1 - UBE2D2 Source Details
RAF1 - CSRP3 Source Details
RAF1 - BCL2 Source Details
GRB10 - RAF1 Target Details
MAP3K5 - RAF1 Target Details
LYN - RAF1 Target Details
RAF1 - SUGT1 Source Details
RAF1 - PRKCE Source Details
YWHAG - RAF1 Target Details
RAP1A - RAF1 Target Details
RAF1 - AGGF1 Source Details
RAF1 - RFXANK Source Details
YWHAQ - RAF1 Target Details
RAF1 - YWHAB Source Details
JAK1 - RAF1 Target Details
RAF1 - CDC25A Source Details
GCG - RAF1 Target Details
RAF1 - BIRC7 Source Details
RAF1 - BFAR Source Details
GRB2 - RAF1 Target Details
RAF1 - PACSIN3 Source Details
RAF1 - ASAP3 Source Details
CNKSR2 - RAF1 Target Details
RAF1 - PHAX Source Details
MAPK1 - RAF1 Target Details
RAF1 - GRB10 Source Details
MYBPC1 - RAF1 Target Details
RAF1 - RBBP8 Source Details
ARRB2 - RAF1 Target Details
PRDX1 - RAF1 Target Details
RAF1 - BAD Source Details
PAK5 - RAF1 Target Details
BCL6 - RAF1 Target Details
PEBP1 - RAF1 Target Details
RAF1 - ADCY6 Source Details
KSR1 - RAF1 Target Details
RAF1 - RBL2 Source Details
RAF1 - HRAS Source Details
RAF1 - NUDCD3 Source Details
RAF1 - BRAF Source Details
MIR195 - RAF1 Target Details
RAF1 - TNNT2 Source Details
TSC22D3 - RAF1 Target Details
GKN2 - RAF1 Target Details
RAF1 - SH3KBP1 Source Details
CKM - RAF1 Target Details
RAF1 - SOX10 Source Details
RAF1 - MAPK3 Source Details
RAF1 - GNB2 Source Details
GNB2 - RAF1 Target Details
RAF1 - NUDT14 Source Details
RAF1 - BRAP Source Details
GNG4 - RAF1 Target Details
RAF1 - RASSF1 Source Details
RAF1 - OTUD7B Source Details
PRKDC - RAF1 Target Details
RAF1 - STUB1 Source Details
ERAS - RAF1 Target Details
RAF1 - KLF10 Source Details
RAF1 - RIPK2 Source Details
RAF1 - KSR1 Source Details
CPS1 - RAF1 Target Details
KRAS - RAF1 Target Details
AKT1 - RAF1 Target Details
RAF1 - PLK3 Source Details
KRT18 - RAF1 Target Details
RAF1 - YWHAH Source Details
RAF1 - RASD2 Source Details
NRAS - RAF1 Target Details
BCL2 - RAF1 Target Details
PAK2 - RAF1 Target Details
PPP1R12A - RAF1 Target Details
MLF1 - RAF1 Target Details
RAF1 - SRF Source Details
YWHAH - RAF1 Target Details
AIRE - RAF1 Target Details
RAF1 - SPRY4 Source Details
RAF1 - LATS2 Source Details
RAF1 - PBK Source Details
PRKCG - RAF1 Target Details
RAF1 - MAP4K1 Source Details
NFATC3 - RAF1 Target Details
RAF1 - SPRY2 Source Details
CASP9 - RAF1 Target Details
EIF4B - RAF1 Target Details
HGF - RAF1 Target Details
LCK - RAF1 Target Details
MAP2K6 - RAF1 Target Details
RPS6KA3 - RAF1 Target Details
RAF1 - PPP1R12A Source Details
PRMT5 - RAF1 Target Details
LOX - RAF1 Target Details
RAF1 - EEF1A2 Source Details
HSP90AB1 - RAF1 Target Details
PPP1CC - RAF1 Target Details
IL1B - RAF1 Target Details
CXCL12 - RAF1 Target Details
RAF1 - VDAC1 Source Details
WDR83 - RAF1 Target Details
IL2RB - RAF1 Target Details
RAF1 - PIN1 Source Details
IL2 - RAF1 Target Details
RAF1 - RAF1 Source Details
RAF1 - RAF1 Target Details
CDKN2A - RAF1 Target Details
RAF1 - MRAS Source Details
RAF1 - OIP5 Source Details
RAF1 - SHOC2 Source Details
CNKSR1 - RAF1 Target Details
CCND2 - RAF1 Target Details
EFEMP1 - RAF1 Target Details
PRKACB - RAF1 Target Details
AKT3 - RAF1 Target Details
CALU - RAF1 Target Details
RAF1 - ABCB5 Source Details
RAF1 - CDC37 Source Details
RAF1 - FKBPL Source Details
PAK3 - RAF1 Target Details
APPL1 - RAF1 Target Details
PAK6 - RAF1 Target Details
RAF1 - PHB Source Details
RAF1 - EIF4H Source Details
CDK4 - RAF1 Target Details
RAF1 - STK26 Source Details
NEUROD1 - RAF1 Target Details
RAF1 - RRAS2 Source Details
CAMK2G - RAF1 Target Details
RAF1 - RHEB Source Details
PRKACA - RAF1 Target Details
PKN1 - RAF1 Target Details
PRKAA2 - RAF1 Target Details
RAF1 - MAPK1 Source Details
MAP2K3 - RAF1 Target Details
RAF1 - MTA1 Source Details
PAK1 - RAF1 Target Details
FGFR4 - RAF1 Target Details
PRKAA1 - RAF1 Target Details
PPP2R5C - RAF1 Target Details
RAF1 - GLIS2 Source Details
FYN - RAF1 Target Details
ETS2 - RAF1 Target Details
RAF1 - CASP9 Source Details
DMPK - RAF1 Target Details
RAF1 - CNKSR1 Source Details
PARK7 - RAF1 Target Details
GATA2 - RAF1 Target Details
Collections
The protein is currently assigned to 46 collections.
# Collection Links
Essential genes for cell-line HPAC Details
Mutated genes for cell-line WM35 Details
Essential genes for cell-line MDA-MB-361 Details
Mutated genes for cell-line KO52 Details
Mutated genes for cell-line UPCISCC152 Details
Essential genes for cell-line IMIM-PC-2 Details
Mutated genes for cell-line MZ2MEL Details
Essential genes for cell-line Hs_578T Details
Mutated genes for cell-line 921 Details
Mutated genes for cell-line HT144SKINFV1 Details
Essential genes for cell-line Hs_766T Details
Mutated genes for cell-line HOP62 Details
Essential genes for cell-line IMIM-PC-1 Details
Mutated genes for cell-line PA1 Details
Mutated genes for cell-line HCC1588 Details
Mutated genes for cell-line NEC8 Details
Mutated genes for cell-line C99 Details
Mutated genes for cell-line HT144SKINFV2 Details
DrugBank drug-targets for investigational drugs Details
Essential genes for cell-line AsPC-1 Details
Mutated genes for cell-line HT144 Details
Mutated genes for cell-line HOUAI Details
Mutated genes for cell-line RCCJF Details
DrugBank drug-targets for small molecule drugs Details
Essential genes for cell-line MDA-MB-157 Details
Mutated genes for cell-line HDMYZ Details
Mutated genes for cell-line CHAGOK1 Details
Mutated genes for cell-line HCC202 Details
Mutated genes for cell-line CAL148 Details
Mutated genes for cell-line KMH2 Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line MFHINO Details
Essential genes for cell-line HCC1143 Details
Essential genes for cell-line HCC38 Details
Essential genes for cell-line TOV-1946 Details
Mutated genes for cell-line CAOV4 Details
Mutated genes for cell-line LS513 Details
Mutated genes for cell-line L363 Details
Mutated genes for cell-line CAL51 Details
Mutated genes for cell-line HT144SKINFV3 Details
Mutated genes for cell-line NCIH2087 Details
Mutated genes for cell-line NO10 Details
Essential genes for cell-line ZR-75-1 Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line FADU Details
Mutated genes for cell-line MESSA Details