Available data Protein details
MAP2K1
6054f78d-dea5-4fcd-853d-0857dff24dd7
Targeting drugs
The protein is currently assigned to 6 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB05239 Details Details
DrugBank Drug ID DB08911 Details Details
DrugBank Drug ID DB11689 Details Details
DrugBank Drug Name Cobimetinib Details -
DrugBank Drug Name Selumetinib Details -
DrugBank Drug Name Trametinib Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Interactions
The protein is currently assigned to 196 interactions.
# Interaction Type Links
MAP2K1 - AURKA Source Details
MAP2K1 - BTRC Source Details
SMAD2 - MAP2K1 Target Details
MAP2K1 - TAL1 Source Details
MAP2K1 - JAK2 Source Details
MAP2K1 - MYOD1 Source Details
MAP2K1 - HSPB8 Source Details
MAP2K1 - PKM Source Details
CLASP1 - MAP2K1 Target Details
RPS6KA3 - MAP2K1 Target Details
EGR1 - MAP2K1 Target Details
MAP2K1 - MAP2K2 Source Details
MAP3K8 - MAP2K1 Target Details
MAP2K1 - LAMTOR3 Source Details
ADRA2A - MAP2K1 Target Details
MAP2K1 - SPAG6 Source Details
MAP2K1 - PTPRJ Source Details
MAP2K1 - RAP1GDS1 Source Details
IQGAP1 - MAP2K1 Target Details
MAP2K1 - MIR497HG Source Details
MAP2K1 - PEBP1 Source Details
MAP3K1 - MAP2K1 Target Details
GPI - MAP2K1 Target Details
CTNND2 - MAP2K1 Target Details
MAP2K1 - KSR1 Source Details
MAP2K1 - RPS6KA4 Source Details
PLK1 - MAP2K1 Target Details
MAP2K1 - YAP1 Source Details
ARVCF - MAP2K1 Target Details
RAF1 - MAP2K1 Target Details
BAX - MAP2K1 Target Details
MAP2K1 - PKP4 Source Details
PPP2CA - MAP2K1 Target Details
MIR497HG - MAP2K1 Target Details
ODC1 - MAP2K1 Target Details
MAP2K1 - DUSP1 Source Details
SRC - MAP2K1 Target Details
MAP2K1 - PARVA Source Details
DAPP1 - MAP2K1 Target Details
ZHX2 - MAP2K1 Target Details
MAP2K1 - TGFBR2 Source Details
PDPK1 - MAP2K1 Target Details
MAP3K21 - MAP2K1 Target Details
MAP2K1 - RBM33 Source Details
MAP2K1 - TP53 Source Details
KPNA5 - MAP2K1 Target Details
MAP2K1 - MAPK3 Source Details
MAP2K1 - STAT3 Source Details
MAP2K1 - VRK2 Source Details
FGB - MAP2K1 Target Details
CTNND1 - MAP2K1 Target Details
MYC - MAP2K1 Target Details
MAP2K1 - TRIB1 Source Details
MAP2K1 - PLEKHF2 Source Details
KRT8 - MAP2K1 Target Details
MAP2K1 - SRC Source Details
ELK1 - MAP2K1 Target Details
MAP2K1 - SKA3 Source Details
CTNNB1 - MAP2K1 Target Details
HGF - MAP2K1 Target Details
ETS1 - MAP2K1 Target Details
MAP2K1 - RNASE9 Source Details
BCKDK - MAP2K1 Target Details
NEK3 - MAP2K1 Target Details
MAP2K1 - DCP1A Source Details
PAK2 - MAP2K1 Target Details
MAP2K1 - SMAD2 Source Details
PAK1 - MAP2K1 Target Details
PEBP1 - MAP2K1 Target Details
MAP2K1 - LAMTOR2 Source Details
MAP2K1 - UBE2I Source Details
LSP1 - MAP2K1 Target Details
MAP2K1 - WDR83 Source Details
PPARG - MAP2K1 Target Details
MAP2K1 - NR1I2 Source Details
YBX1 - MAP2K1 Target Details
CDKN1A - MAP2K1 Target Details
MAP2K1 - RAF1 Source Details
MAP2K1 - RNASE3 Source Details
MAP2K1 - TCP11 Source Details
WDR83 - MAP2K1 Target Details
CTNNA1 - MAP2K1 Target Details
MAP2K1 - PPARG Source Details
PAK3 - MAP2K1 Target Details
MAP3K4 - MAP2K1 Target Details
HSF1 - MAP2K1 Target Details
MAP2K1 - STK11 Source Details
MAPK1 - MAP2K1 Target Details
MAP2K1 - HSF1 Source Details
GIT1 - MAP2K1 Target Details
MAP2K1 - FBXW7 Source Details
E2F4 - MAP2K1 Target Details
MAP2K1 - BAD Source Details
KSR1 - MAP2K1 Target Details
MAP2K1 - BIRC6 Source Details
PIN1 - MAP2K1 Target Details
CDH1 - MAP2K1 Target Details
MAP2K1 - ARMC6 Source Details
MAP2K1 - CTCF Source Details
MAP2K1 - BRAF Source Details
MAP2K1 - UBTF Source Details
MAP2K1 - GSK3B Source Details
MAP2K1 - MAPK14 Source Details
LAMTOR3 - MAP2K1 Target Details
CREBBP - MAP2K1 Target Details
PDGFRL - MAP2K1 Target Details
PIK3CA - MAP2K1 Target Details
MAP2K1 - ARMC8 Source Details
MAP2K1 - MAP2K1 Source Details
MAP2K1 - MAP2K1 Target Details
MAP2K1 - MAP3K1 Source Details
MAP2K1 - KPNA6 Source Details
PIK3R1 - MAP2K1 Target Details
MAP2K1 - PAK1 Source Details
MAP2K1 - PEBP4 Source Details
MAP2K1 - IQGAP1 Source Details
APC - MAP2K1 Target Details
MAP2K1 - TLR2 Source Details
ERBB2 - MAP2K1 Target Details
MAP2K1 - YWHAZ Source Details
MAP2K1 - ARMC3 Source Details
CDKN2A - MAP2K1 Target Details
MAP2K1 - ARMC7 Source Details
MAP2K1 - CTTN Source Details
MAP2K1 - PLCB1 Source Details
MAP2K1 - KSR2 Source Details
CDK5 - MAP2K1 Target Details
MAP2K1 - UBC Source Details
MAP2K1 - MLH3 Source Details
PKP2 - MAP2K1 Target Details
MAP2K1 - BANP Source Details
AR - MAP2K1 Target Details
MAP2K1 - PKP3 Source Details
MAP2K1 - FOXM1 Source Details
EGFR - MAP2K1 Target Details
MAP2K1 - KRT8 Source Details
KPNA1 - MAP2K1 Target Details
HNRNPD - MAP2K1 Target Details
NFE2L2 - MAP2K1 Target Details
BRAP - MAP2K1 Target Details
MAP2K1 - MAPK1 Source Details
MAP2K1 - PSMD10 Source Details
GSK3B - MAP2K1 Target Details
KSR2 - MAP2K1 Target Details
MAP2K1 - VCP Source Details
MAP2K1 - ARRB2 Source Details
HRAS - MAP2K1 Target Details
MAP2K1 - MAPK6 Source Details
BMPR1A - MAP2K1 Target Details
BMI1 - MAP2K1 Target Details
HSPA8 - MAP2K1 Target Details
MAP2K1 - EGR1 Source Details
MAP2K1 - CTCFL Source Details
MAP3K7 - MAP2K1 Target Details
CHEK1 - MAP2K1 Target Details
MSH6 - MAP2K1 Target Details
MAP2K1 - ARMC1 Source Details
MAP2K1 - NUFIP1 Source Details
ARRB2 - MAP2K1 Target Details
MAP2K1 - YWHAB Source Details
CDK1 - MAP2K1 Target Details
MAP2K1 - MAPK8IP3 Source Details
MAP2K1 - FOXP3 Source Details
SHH - MAP2K1 Target Details
MAP2K1 - CFLAR Source Details
MAP2K1 - TRIB3 Source Details
MAP2K1 - TRAF6 Source Details
MAP2K1 - PTK2 Source Details
MAPK3 - MAP2K1 Target Details
MAP2K1 - IRS1 Source Details
MAP2K1 - CASP9 Source Details
MAP2K1 - WNK1 Source Details
MAP2K1 - SPIB Source Details
MAP2K1 - ZNF277 Source Details
MAP2K1 - MAP3K2 Source Details
MAP2K1 - ZFYVE28 Source Details
MAP2K1 - RPS6KA2 Source Details
MAP2K1 - ANKAR Source Details
BRAF - MAP2K1 Target Details
MAP2K1 - ARAF Source Details
ARAF - MAP2K1 Target Details
MAP2K1 - THOC2 Source Details
GRB10 - MAP2K1 Target Details
KRT17 - MAP2K1 Target Details
MAP2K1 - RB1 Source Details
MAP2K1 - BRAP Source Details
PRKCD - MAP2K1 Target Details
MAP3K2 - MAP2K1 Target Details
MAP2K1 - EGFR Source Details
BUB1 - MAP2K1 Target Details
PDK1 - MAP2K1 Target Details
MOS - MAP2K1 Target Details
MAP3K11 - MAP2K1 Target Details
PTK2 - MAP2K1 Target Details
MAPK14 - MAP2K1 Target Details
PPP2CB - MAP2K1 Target Details
Collections
The protein is currently assigned to 59 collections.
# Collection Links
Essential genes for cell-line BT-549 Details
Mutated genes for cell-line SW48 Details
Mutated genes for cell-line ES2 Details
Mutated genes for cell-line OCUM1 Details
Essential genes for cell-line MDA-MB-361 Details
Mutated genes for cell-line PF382 Details
Mutated genes for cell-line SUDHL5 Details
Mutated genes for cell-line HCC364 Details
Essential genes for cell-line OVCA1369_TR Details
Mutated genes for cell-line R256 Details
Mutated genes for cell-line MZ2MEL Details
Mutated genes for cell-line R262 Details
Essential genes for cell-line TOV-2223G Details
Mutated genes for cell-line NCIH1437 Details
Essential genes for cell-line KP-3 Details
Essential genes for cell-line BxPC-3 Details
Essential genes for cell-line Panc_03 Details
Mutated genes for cell-line HEC116 Details
Essential genes for cell-line OVCAR-3 Details
Mutated genes for cell-line BLUE1 Details
Mutated genes for cell-line NCIH460 Details
DrugBank drug-targets for investigational drugs Details
Mutated genes for cell-line OS252 Details
Mutated genes for cell-line JHH5 Details
Mutated genes for cell-line P30OHK Details
Mutated genes for cell-line ECC2 Details
Mutated genes for cell-line LK2 Details
Mutated genes for cell-line PACADD137 Details
Mutated genes for cell-line ES4 Details
Mutated genes for cell-line MOLT4 Details
Mutated genes for cell-line HCA1 Details
DrugBank drug-targets for small molecule drugs Details
Mutated genes for cell-line SNUC1 Details
Essential genes for cell-line EFM-19 Details
Mutated genes for cell-line CAL148 Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line HSKTC Details
Mutated genes for cell-line HHUA Details
Mutated genes for cell-line MCC26 Details
Essential genes for cell-line TOV-3133G Details
Mutated genes for cell-line SCC3 Details
Mutated genes for cell-line BT12 Details
Mutated genes for cell-line SET2 Details
Mutated genes for cell-line A2058 Details
Mutated genes for cell-line SARC9371 Details
Mutated genes for cell-line CORL321 Details
Mutated genes for cell-line HSC3 Details
Mutated genes for cell-line SNGM Details
Mutated genes for cell-line H3118 Details
Mutated genes for cell-line MOLT16 Details
Essential genes for cell-line HCC1395 Details
Mutated genes for cell-line CL34 Details
Essential genes for cell-line ZR-75-1 Details
Mutated genes for cell-line KPNYN Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line DND41 Details
Essential genes for cell-line MDA-MB-231 Details
Mutated genes for cell-line LNCAPCLONEFGC Details
Mutated genes for cell-line HS936T Details