Available data Protein details
JAK1
059924b0-cf50-4a37-8665-1edc55558839
Targeting drugs
The protein is currently assigned to 8 targeting drug values.
# Data Value Internal External
DrugBank Drug ID DB08877 Details Details
DrugBank Drug ID DB08895 Details Details
DrugBank Drug ID DB11817 Details Details
DrugBank Drug ID DB15091 Details Details
DrugBank Drug Name Baricitinib Details -
DrugBank Drug Name Ruxolitinib Details -
DrugBank Drug Name Tofacitinib Details -
DrugBank Drug Name Upadacitinib Details -
Databases
The protein is currently assigned to 6 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
DrugBank Details
Interactions
The protein is currently assigned to 115 interactions.
# Interaction Type Links
MAP3K5 - JAK1 Target Details
IL6R - JAK1 Target Details
JAK1 - PTPN11 Source Details
SOCS3 - JAK1 Target Details
PTPRC - JAK1 Target Details
ISG15 - JAK1 Target Details
IL21R - JAK1 Target Details
GHR - JAK1 Target Details
STAT3 - JAK1 Target Details
IL6ST - JAK1 Target Details
IL15RA - JAK1 Target Details
JAK1 - JAK2 Source Details
JAK1 - IRS2 Source Details
JAK1 - IL7R Source Details
JAK1 - SHC1 Source Details
JAK1 - IL3RA Source Details
JAK1 - IL4R Source Details
FES - JAK1 Target Details
CNTFR - JAK1 Target Details
JAK1 - GRB2 Source Details
JAK1 - PRKCZ Source Details
JAK1 - IL21R Source Details
IL2RB - JAK1 Target Details
TIRAP - JAK1 Target Details
IFNGR2 - JAK1 Target Details
PTPN6 - JAK1 Target Details
IL4R - JAK1 Target Details
STAM2 - JAK1 Target Details
PRKAA1 - JAK1 Target Details
JAK1 - STAM2 Source Details
JAK3 - JAK1 Target Details
IFNLR1 - JAK1 Target Details
SRC - JAK1 Target Details
PTPN2 - JAK1 Target Details
JAK1 - IFNAR2 Source Details
JAK1 - JAK1 Source Details
JAK1 - JAK1 Target Details
IL5RA - JAK1 Target Details
IFNAR2 - JAK1 Target Details
JAK1 - IL6R Source Details
JAK1 - PLCG2 Source Details
JAK1 - PLA2G4A Source Details
IRS2 - JAK1 Target Details
PRKCZ - JAK1 Target Details
IL20RB - JAK1 Target Details
JAK1 - TNFRSF1A Source Details
JAK1 - IFNGR2 Source Details
IL22RA1 - JAK1 Target Details
JAK1 - IL2RG Source Details
PLCG2 - JAK1 Target Details
IL10RB - JAK1 Target Details
EGFR - JAK1 Target Details
CSF3R - JAK1 Target Details
JAK1 - SOCS1 Source Details
JAK1 - STAT5A Source Details
EIF2AK2 - JAK1 Target Details
JAK1 - EIF2AK3 Source Details
IL2RG - JAK1 Target Details
JAK1 - IFNAR1 Source Details
JAK1 - IRS1 Source Details
JAK1 - IL2RB Source Details
JAK1 - SNX8 Source Details
JAK1 - PIK3R1 Source Details
JAK1 - IL10RA Source Details
LEPR - JAK1 Target Details
CSF2RB - JAK1 Target Details
JAK1 - TEC Source Details
TNFRSF1A - JAK1 Target Details
JAK1 - SHB Source Details
IL31RA - JAK1 Target Details
IFNAR1 - JAK1 Target Details
IL7R - JAK1 Target Details
JAK1 - JAK3 Source Details
JAK1 - STAT3 Source Details
IFNGR1 - JAK1 Target Details
JAK1 - DBP Source Details
JAK1 - SIRT1 Source Details
JAK1 - RAF1 Source Details
IL10RA - JAK1 Target Details
TYK2 - JAK1 Target Details
JAK1 - CSF2RB Source Details
JAK1 - RACK1 Source Details
JAK1 - PLAUR Source Details
JAK1 - IFNGR1 Source Details
JAK1 - MAP3K5 Source Details
JAK2 - JAK1 Target Details
JAK1 - IL5RA Source Details
IL9R - JAK1 Target Details
IRS1 - JAK1 Target Details
JAK1 - EIF2AK2 Source Details
JAK1 - FES Source Details
JAK1 - STAT2 Source Details
STAT1 - JAK1 Target Details
LIFR - JAK1 Target Details
JAK1 - TYK2 Source Details
JAK1 - PIK3R2 Source Details
JAK1 - TSHR Source Details
JAK1 - STAT6 Source Details
JAK1 - STAT5B Source Details
JAK1 - INPP5D Source Details
JAK1 - PTPN6 Source Details
OSMR - JAK1 Target Details
JAK1 - IL6ST Source Details
PTPN11 - JAK1 Target Details
IFNB1 - JAK1 Target Details
ERBB2 - JAK1 Target Details
LCK - JAK1 Target Details
JAK1 - PTK2B Source Details
JAK1 - STAT1 Source Details
JAK1 - SOCS3 Source Details
SOCS1 - JAK1 Target Details
IL20RA - JAK1 Target Details
JAK1 - IL9R Source Details
IL3RA - JAK1 Target Details
JAK1 - SYP Source Details
Collections
The protein is currently assigned to 101 collections.
# Collection Links
Mutated genes for cell-line EM2 Details
Mutated genes for cell-line NCIH1385 Details
Mutated genes for cell-line TOV21G Details
Mutated genes for cell-line HT55 Details
Mutated genes for cell-line HEC1A Details
Mutated genes for cell-line SJRH30 Details
Mutated genes for cell-line LB831BLC Details
Mutated genes for cell-line RS5 Details
Mutated genes for cell-line ES2 Details
Mutated genes for cell-line NCIH2882 Details
Mutated genes for cell-line PF382 Details
Mutated genes for cell-line CCK81 Details
Mutated genes for cell-line MOLM6 Details
Mutated genes for cell-line NCIH2066 Details
Mutated genes for cell-line HSC39 Details
Mutated genes for cell-line MET2B Details
Mutated genes for cell-line HMCB Details
Mutated genes for cell-line LN18 Details
Mutated genes for cell-line SNU1 Details
Mutated genes for cell-line H357 Details
Mutated genes for cell-line NCIH1563 Details
Mutated genes for cell-line T3M10 Details
Mutated genes for cell-line RL952 Details
Mutated genes for cell-line MFE296 Details
Mutated genes for cell-line HEC116 Details
Mutated genes for cell-line VMRCLCD Details
Mutated genes for cell-line YT Details
Mutated genes for cell-line KMS28PE Details
Mutated genes for cell-line HEC6 Details
Mutated genes for cell-line CHL1 Details
Mutated genes for cell-line IGROV1 Details
Essential genes for cell-line CAL-51 Details
Mutated genes for cell-line NCIH1793 Details
Mutated genes for cell-line DOTC24510 Details
DrugBank drug-targets for investigational drugs Details
Mutated genes for cell-line NCIH2004RT Details
Mutated genes for cell-line HUT78 Details
Mutated genes for cell-line RPMI8226 Details
Mutated genes for cell-line ESS1 Details
Mutated genes for cell-line SNU638 Details
Mutated genes for cell-line OCIM1 Details
Mutated genes for cell-line H9 Details
Mutated genes for cell-line SNUC2A Details
Mutated genes for cell-line AN3CA Details
Mutated genes for cell-line LS180 Details
Mutated genes for cell-line HEKTE Details
Mutated genes for cell-line HGC27 Details
Mutated genes for cell-line PACADD137 Details
Mutated genes for cell-line SNU1066 Details
Mutated genes for cell-line HEC265 Details
Mutated genes for cell-line HCA1 Details
DrugBank drug-targets for small molecule drugs Details
Essential genes for cell-line MDA-MB-157 Details
Mutated genes for cell-line NP5 Details
Mutated genes for cell-line COLO775 Details
Mutated genes for cell-line JHUEM1 Details
Mutated genes for cell-line MDAPCA2B Details
Mutated genes for cell-line KMS28BM Details
Essential genes for cell-line EFM-19 Details
Mutated genes for cell-line LB831EBV Details
Essential genes for cell-line HCC1187 Details
Mutated genes for cell-line LOVO Details
Mutated genes for cell-line MHHNB11 Details
Mutated genes for cell-line HPBALL Details
Mutated genes for cell-line 22RV1 Details
Mutated genes for cell-line OC316 Details
DrugBank drug-targets for all drugs Details
Mutated genes for cell-line MCC13 Details
Mutated genes for cell-line SNU1544 Details
Mutated genes for cell-line SKMG1 Details
Mutated genes for cell-line WM983B Details
Mutated genes for cell-line CALU6 Details
Mutated genes for cell-line CL14 Details
Mutated genes for cell-line SW1116 Details
Mutated genes for cell-line HEC1B Details
Mutated genes for cell-line ONS76 Details
Mutated genes for cell-line KMS27 Details
Mutated genes for cell-line KNS60 Details
Mutated genes for cell-line K2 Details
Mutated genes for cell-line HEC151 Details
Essential genes for cell-line BT-474 Details
Mutated genes for cell-line MM370 Details
Mutated genes for cell-line SW1417 Details
Mutated genes for cell-line 2313287 Details
Mutated genes for cell-line CAL51 Details
Mutated genes for cell-line RH30 Details
Mutated genes for cell-line OC314 Details
Essential genes for cell-line SW527 Details
Mutated genes for cell-line C2BBE1 Details
DrugBank drug-targets for approved drugs Details
Mutated genes for cell-line PK45H Details
Mutated genes for cell-line CACO2 Details
Mutated genes for cell-line SNUC2B Details
Mutated genes for cell-line HPAC Details
Mutated genes for cell-line HEC1 Details
Mutated genes for cell-line MYM12 Details
Mutated genes for cell-line LNCAPCLONEFGC Details
Mutated genes for cell-line ISHIKAWAHERAKLIO02ER Details
Mutated genes for cell-line HCT116 Details
Mutated genes for cell-line FEPD Details
Mutated genes for cell-line T173 Details