Available data Protein details
PLK1
b2d43332-004d-45fc-a37d-82584378c270
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 5 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
InnateDB Details
Values
The protein is currently assigned to 9 values.
# Data Value Internal External
HGNC ID 9077 Details Details
HGNC Symbol PLK1 Details -
HGNC Name polo like kinase 1 Details -
HGNC Alias PLK Details -
Ensembl ID ENSG00000166851 Details Details
UniProt ID P53350 Details Details
UniProt Title PLK1_HUMAN Details -
NCBI ID 5347 Details Details
InnateDB ID 20740 Details Details
Interactions
The protein is currently assigned to 402 interactions.
# Interaction Type Links
PLK1 - DNAAF5 Source Details
PLK1 - RELA Source Details
PLK1 - TUBB3 Source Details
PLK1 - MYT1 Source Details
PLK1 - BRCA1 Source Details
PLK1 - MLX Source Details
PLK1 - KIF2A Source Details
DNM2 - PLK1 Target Details
CCNT1 - PLK1 Target Details
PRKG1 - PLK1 Target Details
PLK1 - MAVS Source Details
DNAJB9 - PLK1 Target Details
PLK1 - FAM131B Source Details
PLK1 - PLK2 Source Details
EIF4B - PLK1 Target Details
PLK1 - PSMA3 Source Details
PLK1 - PLK4 Source Details
PLK1 - TNFSF11 Source Details
PLK1 - MDM2 Source Details
PLK1 - BEX4 Source Details
PLK1 - CDC20B Source Details
PLK1 - PRC1 Source Details
BMX - PLK1 Target Details
PLK1 - RAN Source Details
PIM1 - PLK1 Target Details
CDC20 - PLK1 Target Details
PLK1 - BATF Source Details
PLK1 - STK10 Source Details
PLK1 - NEDD1 Source Details
PLK1 - OPTN Source Details
PLK1 - PTPN1 Source Details
NDUFA10 - PLK1 Target Details
PLK1 - MAD1L1 Source Details
NUAK1 - PLK1 Target Details
PLK1 - CIC Source Details
PLK1 - MIS18A Source Details
PLK1 - TOPORS Source Details
E2F4 - PLK1 Target Details
PLK1 - GET4 Source Details
PLK1 - IKBKB Source Details
PLK1 - TRIOBP Source Details
HSPA4 - PLK1 Target Details
PLK1 - FANCM Source Details
PLK1 - HASPIN Source Details
PLK1 - NUAK1 Source Details
PLK1 - CCNB1 Source Details
HNRNPU - PLK1 Target Details
PLK1 - RAI14 Source Details
PLK1 - ZC3HC1 Source Details
PLK1 - SMC1A Source Details
PLK1 - RNF126 Source Details
PLK1 - MAPK8 Source Details
PLK1 - DIXDC1 Source Details
MST1R - PLK1 Target Details
PLK1 - PSMA2 Source Details
SLK - PLK1 Target Details
GATA1 - PLK1 Target Details
ETS1 - PLK1 Target Details
PLK1 - FBF1 Source Details
PLK1 - NPM1 Source Details
PLK1 - TCERG1 Source Details
MAPKAPK2 - PLK1 Target Details
PLK1 - LRP5L Source Details
PLK1 - MAP2K1 Source Details
PLK1 - PITPNM1 Source Details
PLK1 - STK3 Source Details
MPP2 - PLK1 Target Details
PLK1 - CDCA5 Source Details
PLK1 - MAGED1 Source Details
PLK1 - ORC3 Source Details
PLK1 - BICD2 Source Details
CTNNB1 - PLK1 Target Details
PLK1 - TRAK2 Source Details
PLK1 - KIF23 Source Details
CSN2 - PLK1 Target Details
PLK1 - SNCB Source Details
PLK1 - LRRK1 Source Details
PLK1 - RUVBL1 Source Details
IKBKB - PLK1 Target Details
PLK1 - SIMC1 Source Details
MCM3 - PLK1 Target Details
PLK1 - YAP1 Source Details
PLK1 - SGO1 Source Details
PLK1 - PSMB6 Source Details
PLK1 - BRCA2 Source Details
PLK1 - MRPL55 Source Details
PLK1 - CEP97 Source Details
ATR - PLK1 Target Details
PLK1 - ANAPC4 Source Details
PLK1 - CTNNB1 Source Details
DSG1 - PLK1 Target Details
PLK1 - MAPKAPK2 Source Details
PLK1 - HNRNPU Source Details
ORC2 - PLK1 Target Details
PLK1 - RAD51 Source Details
PLK1 - MAJIN Source Details
PLK1 - PIN1 Source Details
PLK1 - TUT7 Source Details
PLK1 - TP53 Source Details
PLK1 - TOP2A Source Details
PLK1 - RSF1 Source Details
BRCA2 - PLK1 Target Details
PLK1 - CDH1 Source Details
PLK1 - TSC2 Source Details
PLK1 - STK38 Source Details
PRKG2 - PLK1 Target Details
PLK3 - PLK1 Target Details
PPP2CB - PLK1 Target Details
PLK1 - RAF1 Source Details
BORA - PLK1 Target Details
PLK1 - MPRIP Source Details
ODF2 - PLK1 Target Details
PLK1 - SUGT1 Source Details
PLK1 - ANAPC1 Source Details
PLK1 - PSMA4 Source Details
PLK1 - DNHD1 Source Details
PCM1 - PLK1 Target Details
PKMYT1 - PLK1 Target Details
PLK1 - PRDM14 Source Details
PLK1 - FADD Source Details
IRS1 - PLK1 Target Details
STK10 - PLK1 Target Details
PLK1 - SREBF1 Source Details
MYC - PLK1 Target Details
PLK1 - SUN1 Source Details
PLK1 - SVIL Source Details
PLK1 - RAD21 Source Details
PLK1 - MEIKIN Source Details
PLK1 - RXRA Source Details
PLK1 - ECT2 Source Details
PLK1 - STAG2 Source Details
CDK1 - PLK1 Target Details
PLK1 - TSC1 Source Details
PLK1 - REST Source Details
PLK1 - CNTRL Source Details
PLK1 - MYC Source Details
PLK1 - PLEKHG6 Source Details
PLK1 - C6orf136 Source Details
PLK1 - CENPU Source Details
PPP2CA - PLK1 Target Details
PLK1 - USP16 Source Details
PLK1 - CLIP1 Source Details
PLK1 - RICTOR Source Details
PLK1 - PPP1R7 Source Details
PLK1 - RABAC1 Source Details
PLK1 - CHEK2 Source Details
DCTN1 - PLK1 Target Details
PLK1 - BAG6 Source Details
PLK1 - NINL Source Details
PLK1 - ZNF71 Source Details
PAK3 - PLK1 Target Details
FOXO3 - PLK1 Target Details
PPP1R12A - PLK1 Target Details
PLK1 - IFTAP Source Details
AURKA - PLK1 Target Details
PLK1 - BCL2L1 Source Details
PLK1 - ERCC6L Source Details
PLK1 - AKT2 Source Details
PIN1 - PLK1 Target Details
MCM7 - PLK1 Target Details
PLK1 - TPT1 Source Details
PLK1 - PAK5 Source Details
PLK1 - RPS6KA2 Source Details
PLK1 - RAP1GAP Source Details
NEDD9 - PLK1 Target Details
PLK1 - CEP68 Source Details
PLK1 - CHD1L Source Details
PLK1 - MTMR14 Source Details
PLK1 - TUBG1 Source Details
PLK1 - TERF1 Source Details
HSF1 - PLK1 Target Details
PLK1 - CEP55 Source Details
PLK1 - NCAPH2 Source Details
PLK1 - CCDC115 Source Details
PLK1 - EPS15L1 Source Details
PLK1 - PRRC1 Source Details
PLK1 - MTHFR Source Details
PLK1 - VCP Source Details
PLK1 - TOPBP1 Source Details
PLK1 - TP73 Source Details
PLK1 - MRE11 Source Details
PLK1 - TUBA4A Source Details
PLK1 - BCL2 Source Details
PLK1 - RBBP8 Source Details
KIF2A - PLK1 Target Details
PLK1 - PSMA6 Source Details
PLK1 - SACS Source Details
PLK1 - KLHL9 Source Details
PLK1 - ACTL6B Source Details
PLK1 - GTSE1 Source Details
PLK1 - CDS1 Source Details
EP300 - PLK1 Target Details
PLK1 - IRS2 Source Details
PLK1 - KLHL22 Source Details
PLK1 - RIOK2 Source Details
PLK1 - RRM2 Source Details
PLK1 - NEK9 Source Details
PLK1 - MAP9 Source Details
CDC25B - PLK1 Target Details
PLK1 - CEP162 Source Details
PLK1 - DCAF11 Source Details
PLK1 - UHMK1 Source Details
LTBR - PLK1 Target Details
PLK1 - UBC Source Details
PLK1 - CDK5RAP2 Source Details
NPM1 - PLK1 Target Details
PLK1 - CDC16 Source Details
PLK1 - MTMR3 Source Details
PLK1 - CEP43 Source Details
PLK1 - INTS11 Source Details
PLK1 - HMMR Source Details
PLK1 - SUZ12 Source Details
TSC2 - PLK1 Target Details
PLK1 - CRELD2 Source Details
ATM - PLK1 Target Details
PLK1 - EED Source Details
PLK1 - PSMA1 Source Details
PLK1 - VRK3 Source Details
MAP3K8 - PLK1 Target Details
BRF1 - PLK1 Target Details
PLK1 - TP53BP2 Source Details
PLK1 - PTEN Source Details
PLK1 - TANK Source Details
PLK1 - PRKN Source Details
PLK1 - SNCA Source Details
MCM2 - PLK1 Target Details
PLK1 - DCTN6 Source Details
PLK1 - PKMYT1 Source Details
PLK1 - HMCES Source Details
PLK1 - BORA Source Details
ARHGAP5 - PLK1 Target Details
PLK1 - PSMB3 Source Details
PLK1 - NPHP1 Source Details
PLK1 - KIF2C Source Details
INCENP - PLK1 Target Details
PLK1 - FAM53C Source Details
PLK1 - NOS1AP Source Details
GATA2 - PLK1 Target Details
PLK1 - OFD1 Source Details
PLK1 - FEZ1 Source Details
PLK1 - C1orf226 Source Details
PLK1 - STXBP4 Source Details
PLK1 - PINX1 Source Details
EIF6 - PLK1 Target Details
PLK1 - PCNT Source Details
PLK1 - BRF1 Source Details
PLK1 - PSMB5 Source Details
PLK1 - SATB2 Source Details
PLK1 - MOK Source Details
PLK2 - PLK1 Target Details
CDC6 - PLK1 Target Details
PLK1 - ESPL1 Source Details
PLK1 - PTK2 Source Details
ERCC4 - PLK1 Target Details
PLK1 - DRICH1 Source Details
PLK1 - ITSN1 Source Details
CDC25C - PLK1 Target Details
PLK1 - DCTN1 Source Details
PLK1 - AURKB Source Details
PLK1 - TP53I3 Source Details
PLK1 - CDC23 Source Details
PLK1 - ANAPC7 Source Details
PDPK1 - PLK1 Target Details
BUB1 - PLK1 Target Details
PLK1 - PSMB7 Source Details
PLK1 - ZMYM2 Source Details
MTHFR - PLK1 Target Details
PLK1 - YY1 Source Details
ABL1 - PLK1 Target Details
PLK1 - PTPN14 Source Details
PLK1 - PSMB4 Source Details
PLK1 - NHSL2 Source Details
PLK1 - RPP25L Source Details
PLK1 - WDR62 Source Details
PLK1 - VAMP4 Source Details
PLK1 - CUL2 Source Details
MRE11 - PLK1 Target Details
PLK1 - KRBA1 Source Details
PHC2 - PLK1 Target Details
PLK1 - KDM1A Source Details
PLK1 - LATS1 Source Details
PLK1 - CDC20 Source Details
PLK1 - PLK1 Source Details
PLK1 - PLK1 Target Details
PLK1 - EVI5 Source Details
PAK1 - PLK1 Target Details
PLK1 - TBK1 Source Details
PLK1 - KIF2B Source Details
PLK1 - ATXN10 Source Details
BIRC5 - PLK1 Target Details
PLK1 - NDC80 Source Details
PLK1 - TUBA1A Source Details
PLK1 - CDC25B Source Details
PLK1 - LRRK2 Source Details
PLK1 - SPAG9 Source Details
PLK1 - DVL2 Source Details
HSPA1B - PLK1 Target Details
CYLD - PLK1 Target Details
PLK1 - AXIN2 Source Details
NUDC - PLK1 Target Details
PLK1 - PDS5A Source Details
PLK1 - BIRC6 Source Details
PLK1 - RASGRF1 Source Details
PLK1 - SPOUT1 Source Details
PLK1 - RECQL5 Source Details
PLK1 - KIF20A Source Details
AURKB - PLK1 Target Details
PLK1 - NME7 Source Details
PLK1 - CDC6 Source Details
CDC27 - PLK1 Target Details
PLK1 - MAPK6 Source Details
PLK1 - ZHX1 Source Details
PLK1 - CENPQ Source Details
PLK1 - SLX4 Source Details
PLK1 - CHFR Source Details
PLK1 - SIN3A Source Details
PLK1 - PSMA7 Source Details
PLK1 - CACNG3 Source Details
PLK1 - MUS81 Source Details
PRKN - PLK1 Target Details
CIRBP - PLK1 Target Details
PLK1 - CDC14A Source Details
PLK1 - BIRC5 Source Details
FYN - PLK1 Target Details
DVL2 - PLK1 Target Details
PLK1 - CDC25C Source Details
PLK1 - AURKA Source Details
PLK1 - PRKDC Source Details
PLK1 - IKBKG Source Details
PLK1 - RBX1 Source Details
PLK1 - STIL Source Details
PLK1 - USP37 Source Details
ALK - PLK1 Target Details
PLK1 - KMT2E Source Details
PLK1 - GORASP1 Source Details
PCNT - PLK1 Target Details
BRCA1 - PLK1 Target Details
PLK1 - CCNT1 Source Details
PLK1 - BUB1B Source Details
PLK1 - CEP135 Source Details
CHFR - PLK1 Target Details
FOXM1 - PLK1 Target Details
PLK1 - RGS20 Source Details
OFD1 - PLK1 Target Details
PLK1 - FOXM1 Source Details
GLB1 - PLK1 Target Details
PLK1 - CEP192 Source Details
PLK1 - PPID Source Details
PLK1 - PSMB1 Source Details
PLK1 - IRS1 Source Details
CHEK1 - PLK1 Target Details
PLK1 - VIM Source Details
ATP7A - PLK1 Target Details
PLK1 - SRI Source Details
PLK1 - PSMA5 Source Details
PLK1 - SSX2IP Source Details
PLK1 - AXIN1 Source Details
PLK1 - ORC2 Source Details
NEDD4 - PLK1 Target Details
PLK1 - BUB1 Source Details
BCL2L1 - PLK1 Target Details
MECP2 - PLK1 Target Details
PLK1 - CIP2A Source Details
PLK1 - FBXO5 Source Details
PLK1 - FBXO43 Source Details
PLK1 - WEE1 Source Details
PLK1 - HSF1 Source Details
PLK1 - CALML5 Source Details
PLK1 - CDC27 Source Details
PLK1 - RAD23B Source Details
PLK1 - MAP2K2 Source Details
NINL - PLK1 Target Details
PLK1 - LMO4 Source Details
PLK1 - SCN11A Source Details
PLK1 - ZNF223 Source Details
PLK1 - RNF2 Source Details
PLK1 - KLHL21 Source Details
PITPNA - PLK1 Target Details
CCNB1 - PLK1 Target Details
DSC1 - PLK1 Target Details
APP - PLK1 Target Details
CTBP1 - PLK1 Target Details
PLK1 - PPP6R2 Source Details
PLK1 - ROCK2 Source Details
PLK1 - CLASP2 Source Details
PLK1 - RACGAP1 Source Details
PLK1 - PTPRD Source Details
PLK1 - KAT7 Source Details
PLK1 - TP53BP1 Source Details
PLK1 - CENPJ Source Details
PLK1 - CLSPN Source Details
PLK1 - EIF2AK2 Source Details
PLK1 - KIZ Source Details
CSN1S1 - PLK1 Target Details
PLK1 - NUDC Source Details
PLK1 - FZR1 Source Details
FRY - PLK1 Target Details
PLK1 - TEX14 Source Details
BUB1B - PLK1 Target Details
PLK1 - FBXL5 Source Details
MDM2 - PLK1 Target Details
PLK1 - TMF1 Source Details
Collections
The protein is currently assigned to 99 collections.
# Collection Links
Essential genes for cell-line BT-549 Details
Essential genes for cell-line MDA-MB-436 Details
Mutated genes for cell-line EM2 Details
Mutated genes for cell-line LS1034PBL Details
Essential genes for cell-line SK-OV-3 Details
Mutated genes for cell-line SNUC4 Details
Essential genes for cell-line OV-1946 Details
Mutated genes for cell-line HEC1A Details
Mutated genes for cell-line A204 Details
Mutated genes for cell-line ISTMES2 Details
Essential genes for cell-line MDA-MB-361 Details
Mutated genes for cell-line NCIH1092 Details
Mutated genes for cell-line COLO205 Details
Mutated genes for cell-line CCK81 Details
Mutated genes for cell-line A549 Details
Essential genes for cell-line PaTu_8988S Details
Essential genes for cell-line IMIM-PC-2 Details
Essential genes for cell-line Hs_578T Details
Mutated genes for cell-line BT483 Details
Essential genes for cell-line MCF7 Details
Essential genes for cell-line CFPAC-1 Details
Mutated genes for cell-line SKOV3 Details
Essential genes for cell-line Hs_766T Details
Essential genes for cell-line HCC1419 Details
Essential genes for cell-line KP-3 Details
Essential genes for cell-line T-47D Details
Essential genes for cell-line IMIM-PC-1 Details
Essential genes for cell-line Panc_03 Details
Essential genes for cell-line Capan-2 Details
Essential genes for cell-line HCC1500 Details
Mutated genes for cell-line KYSE30 Details
Essential genes for cell-line CAMA-1 Details
Essential genes for cell-line SK-BR-3 Details
Mutated genes for cell-line IGROV1 Details
Essential genes for cell-line OVCAR-3 Details
Essential genes for cell-line CAL-51 Details
Mutated genes for cell-line REH Details
Essential genes for cell-line HCC1806 Details
Essential genes for cell-line PL45 Details
Essential genes for cell-line MM_OVCAR432_Bast_1 Details
Mutated genes for cell-line C33A Details
Mutated genes for cell-line UACC893 Details
Essential genes for cell-line HCC1937 Details
Essential genes for cell-line OV-90 Details
Mutated genes for cell-line KYM1 Details
Mutated genes for cell-line UDSCC2 Details
Essential genes for cell-line HCC1428 Details
Essential genes for cell-line MIA_PaCa-2 Details
Essential genes for cell-line BT-20 Details
Essential genes for cell-line AsPC-1 Details
Essential genes for cell-line HPDE Details
Mutated genes for cell-line SKCO1 Details
Essential genes for cell-line MDA-MB-157 Details
Mutated genes for cell-line C10 Details
Mutated genes for cell-line ISTSL1 Details
Essential genes for cell-line EFM-19 Details
Mutated genes for cell-line COLO792 Details
Essential genes for cell-line HCC1187 Details
Essential genes for cell-line MDA-MB-468 Details
Mutated genes for cell-line C80 Details
Mutated genes for cell-line KM12 Details
Mutated genes for cell-line SW780 Details
Mutated genes for cell-line HPBALL Details
Mutated genes for cell-line L428 Details
Essential genes for cell-line A2780 Details
Mutated genes for cell-line MCC13 Details
Mutated genes for cell-line SNU1544 Details
Mutated genes for cell-line MFHINO Details
Mutated genes for cell-line SKMG1 Details
Mutated genes for cell-line MDAMB361 Details
Mutated genes for cell-line RI1 Details
Mutated genes for cell-line SW1783 Details
Essential genes for cell-line 609050M Details
Mutated genes for cell-line JHU028 Details
Essential genes for cell-line HCC1143 Details
Mutated genes for cell-line HEC1B Details
Essential genes for cell-line TOV-3133G Details
Essential genes for cell-line OVCA8 Details
Mutated genes for cell-line OACM51 Details
Essential genes for cell-line TOV-1946 Details
Mutated genes for cell-line A2058 Details
Essential genes for cell-line BT-474 Details
Mutated genes for cell-line BCP1 Details
Essential genes for cell-line HCC1395 Details
Mutated genes for cell-line LS1034 Details
Mutated genes for cell-line CORL47 Details
Essential genes for cell-line KPL-1 Details
Essential genes for cell-line SW527 Details
Mutated genes for cell-line COLO201 Details
Essential genes for cell-line MDA-MB-231 Details
Mutated genes for cell-line CBAGPN Details
Essential genes for cell-line OVCA5 Details
Mutated genes for cell-line SUIT2 Details
Mutated genes for cell-line TE1 Details
Mutated genes for cell-line NB17 Details
Mutated genes for cell-line YSCCC Details
Mutated genes for cell-line HEC1 Details
Mutated genes for cell-line ISHIKAWAHERAKLIO02ER Details
Mutated genes for cell-line HCT116 Details