Available data Protein details
TOPBP1
d22da981-1dad-410d-b1ec-fc3931649cd7
Targeting drugs
There are no targeting drug values currently assigned.
Databases
The protein is currently assigned to 4 databases.
# Database Links
HGNC Details
Ensembl Details
UniProt Details
NCBI Details
Values
The protein is currently assigned to 10 values.
# Data Value Internal External
HGNC ID 17008 Details Details
HGNC Symbol TOPBP1 Details -
HGNC Name DNA topoisomerase II binding protein 1 Details -
HGNC Alias Dpb11 Details -
HGNC Alias KIAA0259 Details -
HGNC Alias TOP2BP1 Details -
Ensembl ID ENSG00000163781 Details Details
UniProt ID Q92547 Details Details
UniProt Title TOPB1_HUMAN Details -
NCBI ID 11073 Details Details
Interactions
The protein is currently assigned to 83 interactions.
# Interaction Type Links
CDC45 - TOPBP1 Target Details
RAD1 - TOPBP1 Target Details
HDLBP - TOPBP1 Target Details
TGFA - TOPBP1 Target Details
BLM - TOPBP1 Target Details
ZBTB17 - TOPBP1 Target Details
ACAT1 - TOPBP1 Target Details
TOPBP1 - TICRR Source Details
TOPBP1 - MRPL3 Source Details
TOPBP1 - CDC45 Source Details
GINS1 - TOPBP1 Target Details
BRCA1 - TOPBP1 Target Details
BARD1 - TOPBP1 Target Details
ATRIP - TOPBP1 Target Details
BRIP1 - TOPBP1 Target Details
CDK2 - TOPBP1 Target Details
KMT2A - TOPBP1 Target Details
E2F1 - TOPBP1 Target Details
FANCM - TOPBP1 Target Details
PARP1 - TOPBP1 Target Details
MDC1 - TOPBP1 Target Details
TOPBP1 - SMARCAD1 Source Details
E2F4 - TOPBP1 Target Details
NBN - TOPBP1 Target Details
PLK1 - TOPBP1 Target Details
TOPBP1 - RAD9A Source Details
TOPBP1 - CLSTN1 Source Details
PRICKLE3 - TOPBP1 Target Details
CHEK1 - TOPBP1 Target Details
RAD9A - TOPBP1 Target Details
MUTYH - TOPBP1 Target Details
PTEN - TOPBP1 Target Details
TNFAIP2 - TOPBP1 Target Details
FHL3 - TOPBP1 Target Details
ATR - TOPBP1 Target Details
TOPBP1 - RHNO1 Source Details
TCF20 - TOPBP1 Target Details
TOPBP1 - BRIP1 Source Details
TOPBP1 - TOPBP1 Source Details
TOPBP1 - TOPBP1 Target Details
TOPBP1 - RMI1 Source Details
TOPBP1 - SLX4 Source Details
TOPBP1 - CHEK1 Source Details
TOPBP1 - POLA1 Source Details
TOP2B - TOPBP1 Target Details
TOPBP1 - TEX11 Source Details
TBC1D4 - TOPBP1 Target Details
TOPBP1 - PPHLN1 Source Details
TOPBP1 - ATR Source Details
SF3B2 - TOPBP1 Target Details
ETS1 - TOPBP1 Target Details
CDO1 - TOPBP1 Target Details
TOPBP1 - UBR5 Source Details
POP7 - TOPBP1 Target Details
AR - TOPBP1 Target Details
YBX1 - TOPBP1 Target Details
TOPBP1 - ERI1 Source Details
UBC - TOPBP1 Target Details
PMS2 - TOPBP1 Target Details
EGR1 - TOPBP1 Target Details
TOPBP1 - CBLN4 Source Details
TOPBP1 - TTC31 Source Details
RRBP1 - TOPBP1 Target Details
TOPBP1 - RAD51 Source Details
KMT2D - TOPBP1 Target Details
AKT1 - TOPBP1 Target Details
TOPBP1 - E2F1 Source Details
ATM - TOPBP1 Target Details
PPP1CC - TOPBP1 Target Details
RBBP8 - TOPBP1 Target Details
TOPBP1 - RBM25 Source Details
PML - TOPBP1 Target Details
CLK2 - TOPBP1 Target Details
SMARCA4 - TOPBP1 Target Details
KMT2B - TOPBP1 Target Details
TOPBP1 - DTD1 Source Details
POLE - TOPBP1 Target Details
RAD50 - TOPBP1 Target Details
MSH6 - TOPBP1 Target Details
TOPBP1 - ATRIP Source Details
H1-2 - TOPBP1 Target Details
ABL1 - TOPBP1 Target Details
CALCR - TOPBP1 Target Details
Collections
The protein is currently assigned to 109 collections.
# Collection Links
Mutated genes for cell-line NCIH446 Details
Mutated genes for cell-line SLR21 Details
Mutated genes for cell-line QIMRWIL Details
Mutated genes for cell-line SNU349 Details
Mutated genes for cell-line NTERA2CLD1 Details
Essential genes for cell-line OV-1946 Details
Mutated genes for cell-line BFTC909 Details
Mutated genes for cell-line RAMOS Details
Mutated genes for cell-line RD Details
Mutated genes for cell-line SKMEL31 Details
Mutated genes for cell-line RAMOS2G64C10 Details
Mutated genes for cell-line ST486 Details
Mutated genes for cell-line HT1376 Details
Essential genes for cell-line HPAF-II Details
Mutated genes for cell-line SNU81 Details
Mutated genes for cell-line NCIH1770 Details
Essential genes for cell-line IMIM-PC-2 Details
Essential genes for cell-line Hs_578T Details
Mutated genes for cell-line NCIN87 Details
Mutated genes for cell-line NCIH1437 Details
Mutated genes for cell-line SKOV3 Details
Essential genes for cell-line HCC1419 Details
Mutated genes for cell-line GB1 Details
Essential genes for cell-line T-47D Details
Essential genes for cell-line BxPC-3 Details
Mutated genes for cell-line BE13 Details
Mutated genes for cell-line BICR18 Details
Essential genes for cell-line IMIM-PC-1 Details
Essential genes for cell-line Panc_03 Details
Essential genes for cell-line Capan-2 Details
Mutated genes for cell-line SKMEL30 Details
Mutated genes for cell-line WM2664 Details
Mutated genes for cell-line KMM1 Details
Essential genes for cell-line SK-BR-3 Details
Mutated genes for cell-line NCIH250 Details
Mutated genes for cell-line C125PM Details
Mutated genes for cell-line HEC108 Details
Mutated genes for cell-line A431 Details
Mutated genes for cell-line DBTRG05MG Details
Mutated genes for cell-line WM278 Details
Essential genes for cell-line HCC1806 Details
Mutated genes for cell-line EN Details
Mutated genes for cell-line KKU100 Details
Mutated genes for cell-line MZ1PC Details
Essential genes for cell-line PANC-1 Details
Mutated genes for cell-line SNU175 Details
Mutated genes for cell-line JHH5 Details
Essential genes for cell-line OV-90 Details
Mutated genes for cell-line KYM1 Details
Mutated genes for cell-line WIL2NS Details
Mutated genes for cell-line CW2 Details
Mutated genes for cell-line HEC59 Details
Mutated genes for cell-line HEKTE Details
Mutated genes for cell-line NCIH508 Details
Essential genes for cell-line AsPC-1 Details
Mutated genes for cell-line HEC251 Details
Mutated genes for cell-line SNU719 Details
Mutated genes for cell-line COLO320 Details
Essential genes for cell-line MDA-MB-157 Details
Mutated genes for cell-line NP2 Details
Mutated genes for cell-line NB13 Details
Mutated genes for cell-line MDAPCA2B Details
Mutated genes for cell-line SKMEL2 Details
Mutated genes for cell-line HCC1419 Details
Mutated genes for cell-line CTB1 Details
Mutated genes for cell-line HHUA Details
Mutated genes for cell-line HEC1B Details
Essential genes for cell-line HCC38 Details
Mutated genes for cell-line MDAMB157 Details
Essential genes for cell-line TOV-3133G Details
Mutated genes for cell-line HCC2998 Details
Essential genes for cell-line OVCA8 Details
Mutated genes for cell-line OCIMY5 Details
Mutated genes for cell-line RH18DM Details
Mutated genes for cell-line BT474 Details
Mutated genes for cell-line DAUDI Details
Mutated genes for cell-line K2 Details
Mutated genes for cell-line SCMCRM2 Details
Mutated genes for cell-line CORL321 Details
Mutated genes for cell-line KARPAS45 Details
Mutated genes for cell-line MDAMB134VI Details
Mutated genes for cell-line NCIH630 Details
Mutated genes for cell-line SW1417 Details
Mutated genes for cell-line HARA Details
Essential genes for cell-line HCC1395 Details
Mutated genes for cell-line HT115 Details
Mutated genes for cell-line AML193 Details
Mutated genes for cell-line NCIH2106 Details
Mutated genes for cell-line SSP25 Details
Essential genes for cell-line MDA-MB-453 Details
Mutated genes for cell-line SW1353 Details
Essential genes for cell-line KPL-1 Details
Mutated genes for cell-line NCIBL1437 Details
Mutated genes for cell-line NCIH2085 Details
Essential genes for cell-line SW527 Details
Mutated genes for cell-line PEER Details
Mutated genes for cell-line WM115 Details
Mutated genes for cell-line MG63 Details
Mutated genes for cell-line ISTMEL1 Details
Mutated genes for cell-line FADU Details
Essential genes for cell-line MDA-MB-231 Details
Mutated genes for cell-line PLCPRF5 Details
Mutated genes for cell-line HCC366 Details
Essential genes for cell-line OVCA5 Details
Mutated genes for cell-line NUDHL1 Details
Mutated genes for cell-line CAPAN2 Details
Essential genes for cell-line Panc_04 Details
Essential genes for cell-line Panc_02 Details
Mutated genes for cell-line EPLC272H Details